DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and Adcy7

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_445848.1	Gene:	Adcy7 / 84420	RGDID:	619966	Length:	1100	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	79/270 - (29%)
Similarity:	143/270 - (52%)	Gaps:	40/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 LSRELVMAGWQHCSKLEIM----FEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERM- 479
            |||::     .:..:|:.:    |:||.:..:.:|....|          ||.:::|..:|...
  Rat   833 LSRQI-----DYYCRLDCLWKKKFKKEHEEFETMENVNRL----------LLENVLPAHVAAHFI 882

  Fly   480 --RKSEEHVCQSFEEVSVIFIEV--MNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISP---FV 537
              :.:|:...||::.|.|:|..|  ..::.:..:..::.::.:..||::.:..||.::.|   .|
  Rat   883 GDKAAEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGV 947

  Fly   538 YKVETVGMVYMAVSG-----APDVNPLHAEHA-----CDLALRVMKK---VKAHALPGVAIRVGI 589
            .|::|:|..|||.:|     ..:...|..:|.     .:.::.:|.|   :..|:.....:||||
  Rat   948 EKIKTIGSTYMAAAGLSVPSGHENQDLERKHVHIGVLVEFSMALMSKLDGINRHSFNSFRLRVGI 1012

  Fly   590 NSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVGYKVEARGFVKVK 654
            |.|||:|||:|.:.|:|.::|:|||.||||||:.:...||::..|...:|.:||..|.||.:.||
  Rat  1013 NHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVK 1077

  Fly   655 GKGEMETYWL 664
            ||||:.||::
  Rat  1078 GKGELRTYFV 1087

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	13/62 (21%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	65/195 (33%)
Adcy7	NP_445848.1	AC_N	<21..251	CDD:318454
		Guanylate_cyc	272..422	CDD:306677
		DUF1053	487..593	CDD:399378
		Guanylate_cyc	891..1087	CDD:306677	65/195 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810