DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and si:dkey-37g12.1

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_021333677.1	Gene:	si:dkey-37g12.1 / 796669	ZFINID:	ZDB-GENE-090312-145	Length:	882	Species:	Danio rerio

Alignment Length:	296	Identity:	99/296 - (33%)
Similarity:	166/296 - (56%)	Gaps:	30/296 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 IKDVDSLIFLC---SPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRS 446
            :::::||:..|   :| .|..|..: |...:...:|||:|..:          |:.:..:.||.:
Zfish   598 VEELESLVVSCWRETP-AERPDFSY-IRTAIKKNSPHGVSENI----------LDDLLSRMEQYA 650

  Fly   447 DEL-----EKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDS 506
            ..|     |::.||.:. |::.:.||..|:||.:|.::...:....::::.|::.|.::.. :.:
Zfish   651 CNLEEIVSERTAELQEE-KKRAEGLLTQMLPRSVASQLIAGKTVRAETYDCVTIYFSDIEG-FTA 713

  Fly   507 GSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALR 570
            .|.:: ..||.|..||.:::..|..|....||||||:|..||.|||.|..| ..||:....::|.
Zfish   714 MSASL-TPMQVVNVLNDLYTYFDNIIDYHNVYKVETIGDAYMVVSGLPIRNGDDHAKEIARMSLA 777

  Fly   571 VMKKVKAHALPGV-----AIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQL 630
            :::.:::...|.|     .:|:|::|||.||||||:|:||||||||||||||||||...|..|.:
Zfish   778 IVQGLRSFHSPHVPEQQLRVRIGVHSGPCVAGVVGLKMPRYCLFGDTVNTASRMESYGLPLKIHV 842

  Fly   631 SNYTALKVQKV-GYKVEARGFVKVKGKGEMETYWLL 665
            |:.|...:... .::.|.||.:.:||||.:.|:|||
Zfish   843 SSSTKSLLDTFRNFRCELRGDIHIKGKGWVRTFWLL 878

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	25/101 (25%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	72/183 (39%)
si:dkey-37g12.1	XP_021333677.1	Periplasmic_Binding_Protein_Type_1	<59..258	CDD:324556
		PKc_like	355..628	CDD:328722	7/31 (23%)
		HNOBA	<641..687	CDD:311573	13/46 (28%)
		CYCc	666..850	CDD:214485	70/186 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810