DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gyc89Db and si:ch211-132f19.7

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_688903.4	Gene:	si:ch211-132f19.7 / 560410	ZFINID:	ZDB-GENE-130530-619	Length:	1183	Species:	Danio rerio

Alignment Length:	267	Identity:	82/267 - (30%)
Similarity:	139/267 - (52%)	Gaps:	35/267 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 SRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDE-LLYSMIPRPIA----ERMR 480
            ||:|     :..|:|:.::..  |...|:|...||     |:.:| |||:::|..:|    ||.|
Zfish   875 SRQL-----ETTSRLDFLWRL--QARQEVEDMKEL-----REHNECLLYNILPAHVARHFLERDR 927

  Fly   481 KSEEHVCQSFEEVSVIFIEV--MNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPF---VYKV 540
            .:|:...:|:|.|.|:|..:  .:.|......|...::.:..||::.:..||.:..|:   :.|:
Zfish   928 NNEDLFSESYERVGVMFASIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELLDEPYFQDIEKI 992

  Fly   541 ETVGMVYMAVSG-APDVNPLHAE--HACDLAL------RVMKKVKAHALPGVAIRVGINSGPVVA 596
            :|:|..|||.|| :|:......|  |...|.|      ..:|::.........:||||:.|||||
Zfish   993 KTIGSCYMAASGLSPEKQECEDEWAHLSTLVLFALAMQETLKEINKRTSNDFWLRVGISHGPVVA 1057

  Fly   597 GVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVGYKVEARGFVKVKG----KG 657
            ||:|...|:|.::|.|||.||||:|:.....||:...|:..:.:.|:.::.||.:.|||    :|
Zfish  1058 GVIGATKPQYDIWGMTVNLASRMDSTGLSGRIQVPEATSRVLAEHGFMLQLRGEIYVKGVSERRG 1122

  Fly   658 EMETYWL 664
            .:.||::
Zfish  1123 AVRTYFV 1129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	18/62 (29%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	61/195 (31%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831
		CYCc	338..537	CDD:214485
		Guanylate_cyc	381..559	CDD:278633
		DUF1053	579..667	CDD:283888
		CYCc	903..1103	CDD:214485	63/199 (32%)
		Guanylate_cyc	932..1131	CDD:278633	61/198 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810