DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and CG10738

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_729905.2	Gene:	CG10738 / 39516	FlyBaseID:	FBgn0036368	Length:	1250	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	91/243 - (37%)
Similarity:	142/243 - (58%)	Gaps:	19/243 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 QHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVS 494
            ::.:.||.:.   :.|:|:|::.       |::.|.||:.|:||.:|::::|..:...:.:|:||
  Fly   868 KYANNLEALV---DDRTDQLQEE-------KKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVS 922

  Fly   495 VIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-P 558
            :.|.:::..  :..:.....:|.|..||.:::..|..|....||||||:|..||.|||.|..| .
  Fly   923 IYFSDIVGF--TAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGD 985

  Fly   559 LHAEHACDLALRVMK-----KVKAHALPGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASR 618
            |||.....::|.::.     |::......:.:|:||:||||.|||||:|:|||||||||||||||
  Fly   986 LHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASR 1050

  Fly   619 MESSSDPWMIQLSNYTALKVQKV-GYKVEARGFVKVKGKGEMETYWLL 665
            ||||..|..|..|......:.:: ||....||.:.:||||:..|||||
  Fly  1051 MESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLL 1098

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	13/48 (27%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	75/183 (41%)
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365
		ANF_receptor	67..416	CDD:279440
		PK_GC-A_B	570..853	CDD:270944
		TyrKc	597..847	CDD:197581
		HNOBA	<862..907	CDD:285003	13/48 (27%)
		CYCc	886..1078	CDD:214485	75/200 (38%)
		Guanylate_cyc	913..1099	CDD:278633	77/188 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810