DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gyc89Db and ACXD

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_620469.2	Gene:	ACXD / 38284	FlyBaseID:	FBgn0040507	Length:	1162	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	78/318 - (24%)
Similarity:	138/318 - (43%)	Gaps:	84/318 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 LKGQMFYIKDVDSLIFLCSPLIENLDELHGIGL-YLND--------LNPHGLS---RELVMAGWQ 430
            |:.:::| ::.|::..:.:. |:|.| ...||| .||:        ||.:..|   .::.:|.|.
  Fly   874 LQNELYY-EEYDNVAVMFAS-IKNFD-TDKIGLRVLNEIICDFDDVLNKYSQSLRVEKIKVANWT 935

  Fly   431 HCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSV 495
            :.:...:...:.||.:                             |.:|:         |..||:
  Fly   936 YMAACGLDVSRSEQVN-----------------------------APQMK---------FRNVSL 962

  Fly   496 IFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLH 560
            :.....:.||...::..|.:|.|...|....|||.::     .:.:..|.|   ::..|.::..|
  Fly   963 MPNGRRSRYDGARSSNADGVQRVPYGNGSNIALDLDL-----ERGQYEGNV---ITSGPRISSTH 1019

  Fly   561 ------------AEHACDLALRVMKKVKAHALP---------GVAIRVGINSGPVVAGVVGMKVP 604
                        ||.|.|| :|.|::.....:.         |: :|:||:.|..:|||||:..|
  Fly  1020 NGSSSNEVVRVMAEFALDL-MRTMRRFNTENMQTEYEGSTDYGM-LRIGISHGRAMAGVVGISKP 1082

  Fly   605 RYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKVGYKVEARGFVKVKGKGEMETY 662
            .|.::|:.||.||||:|:..|..||::..||||:::...:...||...|||:|.:.||
  Fly  1083 HYDIWGNPVNMASRMDSTGVPGQIQVTENTALKLREFNIQCNYRGMTFVKGRGNIPTY 1140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	19/112 (17%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	58/196 (30%)
ACXD	NP_620469.2	AC_N	<42..284	CDD:292831
		CYCc	254..476	CDD:214485
		Nucleotidyl_cyc_III	321..503	CDD:299850
		CYCc	856..1117	CDD:214485	70/293 (24%)
		Nucleotidyl_cyc_III	878..1142	CDD:299850	77/314 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453997
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740