DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and rut

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_511156.2	Gene:	rut / 32406	FlyBaseID:	FBgn0003301	Length:	2248	Species:	Drosophila melanogaster

Alignment Length:	305	Identity:	92/305 - (30%)
Similarity:	156/305 - (51%)	Gaps:	46/305 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 DSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSL 453
            |:.:....||  :|..|..|.:::..:..||   .||    :..::|:.:::.  |.|.|.::..
  Fly   868 DNRVNASIPL--HLISLARIAIFMIAILVHG---RLV----EGTARLDFLWQL--QASQEKKEMD 921

  Fly   454 ELADSWKRQGDELLYSMIPRPIA-----ERMRKSEEHVCQSFEEVSVIFIEVMNIYD-----SGS 508
            .|.:|.||    :|::::|..:|     .:.|.:.|...||:.:|.|||..|.|..:     .||
  Fly   922 VLQESNKR----ILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGS 982

  Fly   509 NNIQDAMQAVTTLNKVFSALDE---EIISPFVYKVETVGMVYMAVSG--------APDVNPLHAE 562
            :   ..::.:..||::.:..||   |.....:.|::|||..||||.|        ..|.|.:. .
  Fly   983 D---QGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVR-R 1043

  Fly   563 HACDL-----ALR-VMKKVKAHALPGVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMES 621
            |...|     |:| .::::.:|:.....:|||||.|||||||:|.:.|:|.::|:|||.||||:|
  Fly  1044 HMTALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDS 1108

  Fly   622 SSDPWMIQLSNYTALKVQKVGYKVEARGFVKVKGKGEMETYWLLE 666
            :..|...|::......:....::...||.:||||||:|.||:|.:
  Fly  1109 TGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCD 1153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	21/94 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	68/198 (34%)
rut	NP_511156.2	AC_N	<17..255	CDD:292831
		CYCc	230..425	CDD:214485
		Guanylate_cyc	266..438	CDD:278633
		DUF1053	624..696	CDD:283888
		SLC5-6-like_sbd	<742..>893	CDD:294310	6/26 (23%)
		CYCc	924..1134	CDD:214485	65/217 (30%)
		Guanylate_cyc	954..1151	CDD:278633	68/200 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810