DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and Npr3

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_006232107.1	Gene:	Npr3 / 25339	RGDID:	3196	Length:	652	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	57/283 - (20%)
Similarity:	88/283 - (31%)	Gaps:	112/283 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 LSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGD--------------ELLYSM 470
            ||...:.||:||             :..|......:|.::.:.|:              .||||
  Rat   266 LSAGALAAGFQH-------------KDTEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALLYS- 316

  Fly   471 IPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSN--NIQDAMQAVTTLNKVFSALDEEII 533
                    ..|.|.:...:.|.|..:|.| ..::.|..|  ..:|              ||.:.|
  Rat   317 --------DDKLERNCYFTLEGVHEVFQE-EGLHTSAYNFDETKD--------------LDLDDI 358

  Fly   534 SPFVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVMKKVKAHALPGVAIRVGINSGPVVAGV 598
            ..::...|.|  |.|..||             |...|:|..|..|         |:.||.
  Rat   359 VRYIQGSERV--VIMCASG-------------DTIRRIMLAVHRH---------GMTSGD----- 394

  Fly   599 VGMKVPRYCLFG-DTVNTASRMESSSDPW-------------MIQLSNYTALKVQKVGYK---VE 646
                   |..|. :..|::|..:.|   |             ...|...|.|:..|..::   :|
  Rat   395 -------YAFFNIELFNSSSYGDGS---WKRGDKHDFEAKQAYSSLQTVTLLRTAKPEFEKFSME 449

  Fly   647 ARGFVKVKGKGEMETY--WLLEG 667
            .:..|:.:|..| |.|  ..:||
  Rat   450 VKSSVEKQGLNE-EDYVNMFVEG 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	13/72 (18%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	40/197 (20%)
Npr3	XP_006232107.1	PBP1_NPR_C_like	165..556	CDD:107381	57/283 (20%)
		ANF_receptor	182..535	CDD:279440	57/283 (20%)
		TM_EphA1	587..618	CDD:214014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900