Protein Alignment Gyc89Db and gcy-21

DIOPT Version :9

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001364740.1
• Gene: gcy-21 / 191651
• WormBaseID: WBGene00001546
• Length: 1163
• Species: Caenorhabditis elegans
• Alignment Length: 823
• Identity: 213/823 - (25%)
• Similarity: 310/823 - (37%)
• Gaps: 266/823 - (32%)

  Fly     2 YGMLYESVQHYIQQEYGMETWRKVCQIVDCKHQSFKTHQIYPDKLMPDFAAALSA---------- 56
            ||.:..|:|.|.                   |.|..:|..|  .|.|....|.|:
 Worm   412 YGAIVGSIQIYY-------------------HFSSSSHNSY--SLFPCARLAQSSLLNTVWSLTD 455

  Fly    57 -STGESFDF-----------CMNFFG-RC-------FVRFFSNFGYDKMIRSTGRYFCDFLQSID 101
             |.|.|.||           | .|:| .|       |:          ::.|.|      :..:.
 Worm   456 YSEGLSIDFVNKSAPKDTPVC-GFYGENCGPPANNTFI----------IVISVG------VAVLI 503

  Fly   102 NIHVQMRFTYPKMKSPSM--QLTNMDDDGAVILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTA-- 162
            .:.:...|.|.:.:....  .|..|.|...:||.:.... ||:..:..|..:.........|.
 Worm   504 GLAIAAAFLYKRYRYERRLHSLFFMIDRNQIILKKHTNL-MSQQSLRSMASIHGSVVAASQTLRD 567

  Fly   163 --YVLESQNDI----------CGGTA-----GPIK-----------------------LTEGPLT 187
              :.:|..|:.          .|.||     |||.                       |.|| .|
 Worm   568 SHFFIEDYNNASSINASSIFNTGSTARAGPFGPIPGFGGVTGASEDEKWHQIPDFGVGLYEG-RT 631

  Fly   188 VIVK--YRLDFD----NRDYMAK-----RVNVIAHPSQLKMPSVDLNVFLELF---PFTIVLDHD 238
            |.:|  ||.|.:    .|..:||     ..|||.....: :.|.|:.|..||.   ....:||:|
 Worm   632 VALKRIYRSDVEFTRSIRLEIAKLQESVNSNVIEFVGMV-VQSPDVFVVYELAQRGSLKDILDND 695

  Fly   239 -------MKITLAGEKIVETWILHNPGVNPKTFIGSH----------------ILERFKCR--RP 278
                   .:..:..:.|.....||:   :|   ||.|                .|..|..|  |.
 Worm   696 DMPLDDVFRSQMTKDIIAGLEYLHS---SP---IGCHGRLKSTNCLIDARWMVRLSSFGLRELRG 754

  Fly   279 KDTQIQWETILQMRTVLFEF-ELIR--TGHNRA---------AYDAALNFDFENF-------DEA 324
            ::|..|.:.:.:.:..|:.. ||:|  ||.::.         .|..|:.. :|.|       ||.
 Worm   755 EETWQQEDDVQEGKDQLWTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVL-YELFGRLGPWGDEP 818

  Fly   325 SSLNEAQAM----ALASAKEFSAENA--KE------EAAAAATSKDEIDPATGQRRHSVGLRSIL 377
            ....|..::    |||..|.|..:.|  ||      |...||.::|
 Worm   819 MEPREIVSLVKREALAGKKPFRPDMAVLKESPRIVQETVVAAWTED------------------- 864

  Fly   378 LKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKE 442
                               ||  |...||.|...|..|. .||.|.:          ::.|....
 Worm   865 -------------------PL--NRPSLHQIKRKLKPLT-IGLKRTI----------MDNMVSMI 897

  Fly   443 EQRSDELEKSL----ELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNI 503
            |:.:|:|||.:    |..:..|.:.:.||..|:|..:|:.::.......:|||..:|.|.:....
 Worm   898 EKYTDKLEKDIAERNEELEGEKAKSEALLKMMLPEVVADSLKLGSNVSAESFENCTVFFSDCPGF 962

  Fly   504 YD-SGSNNIQDAMQAVTTLNKVFSALDEEIISPF-VYKVETVGMVYMAVSGAPDVNPLHAEHACD 566
            .: |.::...|.:|.:..|..||    :.||..| ||||||:...||..||.|..|..|  ||.:
 Worm   963 VEMSATSKPIDIVQFLNDLYTVF----DRIIDQFDVYKVETIADAYMVASGLPVPNGNH--HAGE 1021

  Fly   567 LA------LRVMKKVKAHALPG--VAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSS 623
            :|      |:.::..|...||.  |.:|:|:||||.||||||:|:||||||||||||||||||:.
 Worm  1022 IASLGLALLKAVESFKIRHLPNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNG 1086

  Fly   624 DPWMIQLSNYTALKV--QKVGYKVEARGFVKVKGKGEMETYWL 664
            .|..|..|. ||.::  |..||::|.||.|::||||:..||::
 Worm  1087 IPLRINCSG-TAKEILDQLGGYEIEERGIVEMKGKGKQMTYFV 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167	35/190 (18%)
		HNOBA	218..479	CDD:400168	70/323 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	84/189 (44%)
gcy-21	NP_001364740.1	Periplasmic_Binding_Protein_type1	58..422	CDD:415822	4/9 (44%)
		PK_GC	612..881	CDD:270894	68/317 (21%)
		HNOBA	<890..938	CDD:400168	13/47 (28%)
		Guanylate_cyc	944..1130	CDD:306677	84/192 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810