Protein Alignment Gyc89Db and gcy-14

DIOPT Version :10

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_506660.2
• Gene: gcy-14 / 191647
• WormBaseID: WBGene00001540
• Length: 1111
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 147/535 - (27%)
• Similarity: 236/535 - (44%)
• Gaps: 109/535 - (20%)

  Fly   218 PSVDLNVFLELFPFTI-------------VLDHDMKITLAGEKIVETWILHN-PGVNPKTFIGSH 268
            ||....:.:|....||             .:.||:.:....|:..|...:.| ...|...|||..
 Worm   540 PSTSTKITVESRSETINFIFYYYQQDILAAMKHDLILQFDAEQKAEFRQMRNFDNDNLNKFIGLC 604

  Fly   269 I-------LERFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAYDAALNFDFENF----- 321
            :       |.|| |.|...:.:..::.:||.: .|.|.|||...|      .|.|...:|
 Worm   605 LDGPQLFSLWRF-CSRGSLSDVISKSSMQMDS-FFMFSLIRDISN------GLLFIHNSFLKCHG 661

  Fly   322 ---------DEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRR-----HSVG 372
                     |:...: :.....|.|.:.|  ||.|:| ....|..:.:.....:|.     :|.|
 Worm   662 HLTSRCCLIDDRWQI-KISGYGLKSVRTF--ENPKKE-DLLWTPPENLRNENEERLPEGDIYSFG 722

  Fly   373 L--RSILLKGQMFYIKD----VDSLIFLC-----SPLIENLDELHGIGLYLNDLNPHGLSRELVM 426
            :  ..||.:...|.:::    .|.:|:..     :|:..:||....:     ::||..|  .|:.
 Worm   723 IICSEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPMRPSLDTGETV-----EINPALL--HLIR 780

  Fly   427 AGW-----------------------QHCSKLEIMFEKEEQRSDELEKSL-----ELADSWKRQG 463
            ..|                       :..:.::.:|...|..:..||:.:     ||.:. |::.
 Worm   781 DCWTERPSERPSIEQVRGHLNGMRDGRKSNLMDHVFNMLETYASTLEEEVSDRTKELVEE-KKKS 844

  Fly   464 DELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSAL 528
            |.|||.|:|:.:|::::..:....::||:|::.|.:|:........  ...:|.||.||.:::..
 Worm   845 DVLLYRMLPKMVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLAGK--CTPLQVVTLLNDLYTIF 907

  Fly   529 DEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMKKV---KAHALPG--VAIRV 587
            |..|....||||||:|..|:.|||.|..| ..|..|...::|..:..:   :...||.  :.:|:
 Worm   908 DGIIEQNDVYKVETIGDGYLCVSGLPHRNGNEHIRHIARMSLGFLSSLEFFRVQHLPSERINLRI 972

  Fly   588 GINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSNYTALKVQKV--GYKVEARGF 650
            |||.|.|||||||:.:||||||||.|||||||||:..|..|.::......:.:|  |::.|:||.
 Worm   973 GINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGKIHVTAEANQMLTQVVGGFRTESRGE 1037

  Fly   651 VKVKGKGEMETYWLL 665
            |.:||||.|||||||
 Worm  1038 VIIKGKGVMETYWLL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:462233
		HNOBA	218..479	CDD:462234	69/339 (20%)
		Nucleotidyl_cyc_III	488..665	CDD:448371	76/184 (41%)
gcy-14	NP_506660.2	PBP1_NPR_GC-like	21..419	CDD:380575
		Protein Kinases, catalytic domain	535..800	CDD:473864	55/278 (20%)
		HNOBA	<816..860	CDD:462234	14/44 (32%)
		CYCc	839..1031	CDD:214485	71/194 (37%)