Protein Alignment Gyc89Db and phlp-2

DIOPT Version :9

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001337270.1
• Gene: phlp-2 / 185690
• WormBaseID: WBGene00009647
• Length: 1126
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 104/574 - (18%)
• Similarity: 200/574 - (34%)
• Gaps: 189/574 - (32%)

  Fly    73 FVRFFSNFGYDKMIRSTGRYFCD-----------FLQSIDNIHVQM-RFTYPKMKSPSMQLTNMD 125
            |:|.:|:.|.    ||| |..||           |  |.|.|.:|: .:.:.::||.:..|..:.
 Worm    26 FLRLYSSDGQ----RST-RIECDEHTTCAQICQQF--SCDVITLQIGNYHFRQLKSDTSPLAILQ 83

  Fly   126 DDGAVILYRSGRTGMSKYLIGQMTEVAKEFYGLDMTAYVLESQNDICGGTAGPIKLTEGPLTVIV 190
            |...::      |...:.|..:.|..|.|    |:.:|                  |:.|   ..
 Worm    84 DFCRIL------TMSDENLETESTSKALE----DILSY------------------TDSP---AF 117

  Fly   191 KYRLDFDNRDYMAKRVNVIAHPSQLKMPSVDLNVFLELFPFTIVLDHDMKITLAGEKIVETW--- 252
            ::...|           .:..|......:::|::..|            ::.:...|::.||
 Worm   118 RHIFSF-----------FLGRPRIRAKSTLNLDILSE------------EVVIRKGKLIHTWQNA 159

  Fly   253 --ILHNPGVNPKT-------------FIGSHILERFKCRRPKDTQIQWETILQMRTVLFEF---- 298
              :.:|..:..:|             .:..|..:|.:..|.||..:.:..|.|...:|..:
 Worm   160 RAVFYNSNIRLQTKNNQDEALQIRNMKVDVHESKRGRALRLKDDDVCYLIIFQRPNILEAWLTRA 224

  Fly   299 -ELIRTGHNRAAYDAALNFDFENFDEASSL-------NEAQAMAL-ASAKEFSAENAKEEAAAAA 354
             ::.::.|    .||:        ||..:|       |||:...| .......:....|::.|..
 Worm   225 QQVEKSNH----VDAS--------DEQLTLIPEQILNNEARVQILNLRRNSLISRPPTEKSMAPL 277

  Fly   355 TSKDEIDPATGQRRHSV---------------------GLRSILLKGQMFYIKDVDSLIFLCSPL 398
            ...|::     .|.||:                     .||.:.|...  ||..|.|   .||
 Worm   278 GYIDDL-----YRVHSLQVIDLSANQILSFPIQLTLLSHLRQLNLSSN--YISSVPS---ECS-- 330

  Fly   399 IENLDELHGIGLYLNDLN--PHGLSRELVMAGWQHCSKLEIMFEKEEQRSDEL-EKSLELADSWK 460
              |:..|..:.|..|.|:  |..:| ||     |:...|:|.|.:..|....| ..:||:   |:
 Worm   331 --NMRRLQYLNLSNNQLDTLPDSIS-EL-----QNLQSLDISFNQFSQIPPCLFHLTLEM---WR 384

  Fly   461 RQGDELLYSMIPRPIAERMRKSE--------------EHVCQ-SFEEVSVI---------FIEVM 501
            ..|:.:  ..|.|....:::|.:              |::.. ...:.|:|         |::|:
 Worm   385 LAGNNI--EKIDRVGEMQIQKIDLRRNVLDTSFRLDIENITHLDLRDNSMISTVHLTNLRFLKVI 447

  Fly   502 NIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPD 555
            :......:::..:.:::|.:....:.||..::.|....::|:.:.:......||
 Worm   448 HCERLQLSSLHLSGESLTHVYADHNLLDSLVVMPLPQNLQTLSLSFNHFRNLPD 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167	25/99 (25%)
		HNOBA	218..479	CDD:400168	61/315 (19%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	11/78 (14%)
phlp-2	NP_001337270.1	leucine-rich repeat	232..253	CDD:275380	8/32 (25%)
		leucine-rich repeat	254..288	CDD:275380	5/38 (13%)
		PLN00113	283..>718	CDD:331614	46/244 (19%)
		leucine-rich repeat	289..311	CDD:275380	0/21 (0%)
		leucine-rich repeat	312..334	CDD:275380	10/30 (33%)
		leucine-rich repeat	335..357	CDD:275380	8/27 (30%)
		leucine-rich repeat	358..379	CDD:275380	5/20 (25%)
		leucine-rich repeat	380..440	CDD:275380	10/64 (16%)
		leucine-rich repeat	441..485	CDD:275380	6/43 (14%)
		leucine-rich repeat	486..508	CDD:275380	3/16 (19%)
		leucine-rich repeat	509..534	CDD:275380
		leucine-rich repeat	554..577	CDD:275380
		leucine-rich repeat	578..602	CDD:275380
		leucine-rich repeat	603..625	CDD:275380
		leucine-rich repeat	626..649	CDD:275380
		leucine-rich repeat	650..672	CDD:275380
		leucine-rich repeat	673..694	CDD:275380
		PP2Cc	754..985	CDD:214625

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900