Protein Alignment Gyc89Db and Gucy2d

DIOPT Version :9

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001124165.1
• Gene: Gucy2d / 14918
• MGIID: 106030
• Length: 1117
• Species: Mus musculus
• Alignment Length: 577
• Identity: 157/577 - (27%)
• Similarity: 245/577 - (42%)
• Gaps: 133/577 - (23%)

  Fly   166 ESQNDICGGTAGPIKLTEGPL---------TVIVKYRLDFDNRDYMAKRVNVIAHPSQL------ 215
            ||::.:.||:  |..:|:|..         |.:..|:.::.........|.....||.|
Mouse   542 ESRSVVDGGS--PRSVTQGSARSLPAFLEHTNVALYQGEWVWLKKFEAGVAPDLRPSSLSFLRKL 604

  Fly   216 -KMPSVDLNVFLELF----PFTIVLDH----DMKITLAGEKIVETWILHNPGVNPKTFIGSHILE 271
             :|...::..||.||    ...:||:|    .::..|..|.:...|          ||..|.:|:
Mouse   605 REMRHENVTAFLGLFVGPGVSAMVLEHCARGSLEDLLQNENLRLDW----------TFKASLLLD 659

  Fly   272 -----------RFKCRRPKDTQIQWETILQMRTVLFEFELIRTGHNRAAYDAALNFDFENFDEAS 325
                       ||...|.|......:|         .|.|..|.|..|        :|.....:|
Mouse   660 LIRGLRYLHHRRFPHGRLKSRNCVVDT---------RFVLKITDHGYA--------EFLESHCSS 707

  Fly   326 SLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRRHSVGLRSILLKGQMF------- 383
            ....|....|.:|.|......|      ||.|.::...      ::.|:.:|.:...:
Mouse   708 RPQPAPEELLWTAPELLRGPGK------ATFKGDVFSL------AIILQEVLTRDPPYCSWGLSA 760

  Fly   384 --YIKDVDSLIFLCSPLIE------------------------NLDELHGIGLYLNDLNPHGLSR 422
              .|:.|.|...||.||:.                        :||:::   .....:| .|...
Mouse   761 EEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQIY---TQFKSIN-QGKKT 821

  Fly   423 ELVMAGWQHCSKL-EIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHV 486
            .:|.:..:...|. |.:.:..::|::|||  ||     :|:.:.||..|:|..:|..::......
Mouse   822 SVVDSMLRMLEKYSESLEDLVQERTEELE--LE-----RRKTERLLSQMLPPSVAHALKMGTTVE 879

  Fly   487 CQSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVS 551
            .:.|::|::.|.:::..  :..:.:.:.::.|..||.:::..|..:.|..||||||:|..||..|
Mouse   880 PEYFDQVTIYFSDIVGF--TTISALSEPIEVVGFLNDLYTLFDAVLDSHDVYKVETIGDAYMVAS 942

  Fly   552 GAPDVN-PLHAEHACDLALRVMKKV----KAHALPGVAIRV--GINSGPVVAGVVGMKVPRYCLF 609
            |.|..| ..||....:|||.::...    ..|| |.|.|||  |::|||.||||||:.:||||||
Mouse   943 GLPRRNGNRHAAEIANLALDILSYAGNFRMRHA-PDVPIRVRAGLHSGPCVAGVVGLTMPRYCLF 1006

  Fly   610 GDTVNTASRMESSSDPWMIQLSNYT--ALKVQKVGYKVEARGFVKVKGKGEMETYWL 664
            ||||||||||||:..|:.|.:|..|  ||.....|||::.||..::||||..|||||
Mouse  1007 GDTVNTASRMESTGLPYRIHVSQSTVQALLSLDEGYKIDVRGQTELKGKGLEETYWL 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	62/313 (20%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	81/186 (44%)
Gucy2d	NP_001124165.1	PBP1_sensory_GC_DEF-like	71..445	CDD:380594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	529..557		5/16 (31%)
		PK_GC-2D	554..818	CDD:270945	55/306 (18%)
		CYCc	855..1044	CDD:214485	74/191 (39%)
		Interaction with NCALD. /evidence=ECO:0000250|UniProtKB:P51839	874..915		6/42 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1096..1117

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910