DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and gc2

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_021333059.1	Gene:	gc2 / 140425	ZFINID:	ZDB-GENE-011128-8	Length:	1120	Species:	Danio rerio

Alignment Length:	243	Identity:	94/243 - (38%)
Similarity:	142/243 - (58%)	Gaps:	20/243 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 QHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVS 494
            |:.|.||   |...:|::|||  :|     |::.::||..|:|..:||.::.......:.||.||
Zfish   830 QYSSNLE---ELIRERTEELE--IE-----KQKTEKLLTQMLPPSVAEALKLGTTVEPEHFESVS 884

  Fly   495 VIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-P 558
            :.|.:::......:|:  :.::.|..||.:::..|..|.:..||||||:|..||..||.|..| .
Zfish   885 LYFSDIVGFTTISANS--EPIEVVDLLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGN 947

  Fly   559 LHAEHACDLALRVMKKV---KAHALPG--VAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASR 618
            .||....::||.::..|   :...:|.  |.||:|:::||.||||||:.:||||||||||.||||
Zfish   948 RHAAEIANMALDILSAVGTFRMRHMPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASR 1012

  Fly   619 MESSSDPWMIQLSNYTA--LKVQKVGYKVEARGFVKVKGKGEMETYWL 664
            |||:..|:.|.:.:.|.  |...|:||:||.|...::|||...|||||
Zfish  1013 MESTGLPYRIHVHSSTVKILMELKLGYRVELRARTELKGKRIEETYWL 1060

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	17/48 (35%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	77/185 (42%)
gc2	XP_021333059.1	PBP1_sensory_GC_DEF_like	59..440	CDD:107366
		PK_GC-2D	551..815	CDD:270945
		HNOBA	<824..869	CDD:311573	17/48 (35%)
		CYCc	848..1040	CDD:214485	73/198 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810