DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Db and gucy2f

DIOPT Version :9

Sequence 1:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_571939.2	Gene:	gucy2f / 140424	ZFINID:	ZDB-GENE-011128-7	Length:	1107	Species:	Danio rerio

Alignment Length:	244	Identity:	94/244 - (38%)
Similarity:	144/244 - (59%)	Gaps:	20/244 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 QHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVS 494
            |:.|.||.:.   .:|::|||..       |::.::||..|:|..:||.::.......:.|::|:
Zfish   831 QYSSNLEDLI---RERTEELEVE-------KQRTEKLLSEMLPPSVAEALKTGASVEPEYFDQVT 885

  Fly   495 VIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-P 558
            :.|.:::..  :..:::.|.::.|..||.::|..|..:.|..||||||:|..||..||.|..| .
Zfish   886 IYFSDIVGF--TTISSLSDPIEVVDLLNDLYSLFDAVLGSHDVYKVETIGDAYMVASGLPKKNGN 948

  Fly   559 LHAEHACDLALRVMKKV---KAHALP--GVAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASR 618
            .||....:::|.::..|   |...:|  .|.||:||:|||.||||||:.:|||||||||||||||
Zfish   949 KHAAEIANMSLNILSSVGSFKMRHMPEVPVRIRIGIHSGPCVAGVVGLTMPRYCLFGDTVNTASR 1013

  Fly   619 MESSSDPWMI--QLSNYTALKVQKVGYKVEARGFVKVKGKGEMETYWLL 665
            |||:..|:.|  .:|....|:....|||::.||..::||||..|||||:
Zfish  1014 MESTGLPYRIHVNISTVQILRSLNDGYKIDVRGKTELKGKGIEETYWLV 1062

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	15/48 (31%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	78/184 (42%)
gucy2f	NP_571939.2	PBP1_sensory_GC_DEF_like	59..440	CDD:107366
		PK_GC-2D	551..816	CDD:270945
		HNOBA	<825..870	CDD:311573	15/48 (31%)
		CYCc	850..1042	CDD:214485	74/200 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810