Protein Alignment Gyc89Db and gucy1a2

DIOPT Version :9

• Sequence 1: NP_650551.1
• Gene: Gyc89Db / 42002
• FlyBaseID: FBgn0038436
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_009290254.2
• Gene: gucy1a2 / 100330875
• ZFINID: ZDB-GENE-121023-3
• Length: 608
• Species: Danio rerio
• Alignment Length: 652
• Identity: 153/652 - (23%)
• Similarity: 267/652 - (40%)
• Gaps: 187/652 - (28%)

  Fly    54 LSASTGESFDFCM-------NFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHVQMRFTY 111
            |||....|.||..       .|||.|...      .::::|:.|....||....|.:...:|.:.
Zfish     2 LSAHDINSVDFAAIRGRFGEEFFGLCLEE------NERVLRALGGNLQDFFNGFDALLEHIRTSC 60

  Fly   112 PKMKS---PSM---------QLTNMDDDGAVILYRSGRT------------GMSKYLIGQMTEVA 152
            .:..|   ||.         :.||. :.||      |||            |::  :.|.:...|
Zfish    61 GRRASSEAPSFLCKDAPQENEETNA-ESGA------GRTLILHCFNPDPTVGVA--MPGLIRAAA 116

  Fly   153 KEFYGLDMTAYVLESQNDICGGTAGPIKL----TEGPLTVIVKYRLDFDNR-------------- 199
            :..|           |:::....|.|..|    .:|.|:.        |:.
Zfish   117 RRIY-----------QSEVSVEEAPPTWLHTANEDGELSA--------DSSPSSSPSPPSSSAPA 162

  Fly   200 --DYMAKRVNV----IAHPSQLKMPSVDLNV----FLELFPFTIVLDHDMKITLAGEKIVETWIL 254
              .::.:.|:.    .:...||....:||.:    |...|||.:||..:|::...||
Zfish   163 CLSFLIREVHTPPTSSSRSRQLSRSPLDLRIGLSTFCRAFPFHLVLGSNMEVLQVGE-------- 219

  Fly   255 HNPGVNPKTFIGSHILERFKCRRPKDTQIQWETILQMRTVLF--EFELIRTGHNRAAYDAALNFD 317
               |:..:.....|                       ||:.|  .|||:         ...:...
Zfish   220 ---GLRKQAKTDPH-----------------------RTLTFSNSFELV---------SPRIPCS 249

  Fly   318 FENFDEASSLNEAQAMALASAKEFSAENAKEEAAAAATSKDEIDPATGQRRHSVGLRSILLKGQM 382
            |:|.    .|..:....:.:..:.|:.:.:|:.                         :.|||||
Zfish   250 FQNI----LLRLSTPFTIRTRPDGSSLDCREKV-------------------------MELKGQM 285

  Fly   383 FYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSD 447
            .::.:.:|::||.||.::.|:||.|.||:|:|:..|..:|::::.|.|  :|.:...:|   |.|
Zfish   286 LHLPESNSIMFLGSPRVDRLEELMGRGLHLSDIPIHDATRDVILVGEQ--AKAQDGLKK---RMD 345

  Fly   448 E----LEKSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVCQSFEEVSVIFIEVMNIYDSGS 508
            :    |||:.:..:..||:..:||||:.|..:|:|:.:......:.|::|:::|.:::     |.
Zfish   346 KLKATLEKTHQALEEEKRRTVDLLYSIFPGDVAQRLWQGLPVQAKKFDDVTMLFSDIV-----GF 405

  Fly   509 NNI---QDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALR 570
            ..:   ...||.::.||::::..|.:.....|||:||:|..|....|.......||:....:||:
Zfish   406 TAVCAQCTPMQVISMLNELYTRFDYQCGILDVYKIETIGDAYCVAGGLHRKIDSHAKPIALMALK 470

  Fly   571 VMKKVKAHALPG---VAIRVGINSGPVVAGVVGMKVPRYCLFGDTVNTASRMESSSDPWMIQLSN 632
            :|:..:....|.   :.:|:||:||.|:|||||:.:|||||||:.|..||:.||.|.|..|.:|.
Zfish   471 MMELSEEVLTPDGKPIKLRIGIHSGSVLAGVVGVMMPRYCLFGNNVTLASKFESGSHPRCINVSP 535

  Fly   633 YT 634
            .|
Zfish   536 TT 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167	30/137 (22%)
		HNOBA	218..479	CDD:400168	61/270 (23%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	51/153 (33%)
gucy1a2	XP_009290254.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820