DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Da and npr1a

DIOPT Version :9

Sequence 1:NP_001036718.1 Gene:Gyc89Da / 42001 FlyBaseID:FBgn0038435 Length:667 Species:Drosophila melanogaster
Sequence 2:NP_001038402.1 Gene:npr1a / 560653 ZFINID:ZDB-GENE-060503-539 Length:1067 Species:Danio rerio


Alignment Length:453 Identity:136/453 - (30%)
Similarity:216/453 - (47%) Gaps:101/453 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   282 TIDWDTLIQMRAVLFEFELIRTGHNRAAYDAVLNMDFENYDEM----DLNEAQTMALAK------ 336
            |:||         :|.:.||.        |.|..|.|.:...:    :|..:..:..::      
Zfish   636 TLDW---------MFRYSLIN--------DIVKGMAFLHNSVIVSHGNLKSSNCVVDSRFVLKIT 683

  Fly   337 ---AQEFSESHPVDD------------DESAREDEIDPATGERRS---SQGL---RSILLKGQMF 380
               .:.|.:...:||            .|..|.|. .||.|.::.   |.|:   ...|||| :|
Zfish   684 DYGLESFHKDSNLDDVHAFYARQLWTAPELLRADN-PPACGTQKGDVYSFGIILQELALLKG-VF 746

  Fly   381 YIKDVDSLIFLC-SP--LIENLDELHGIGLYLND-LNPHGLSRE---LVMAGWQH-------CSK 431
            |::..      | ||  :||.:.|  |...||.. |.|...|.|   |::..|..       .|:
Zfish   747 YLEGP------CLSPKEIIERVVE--GRWPYLRPLLCPQSHSEEMGQLMLRCWSEDVNERPDFSQ 803

  Fly   432 LEIMFEKE----------------EQRSDELEKSLE----LADSWKRQGDELLYSMIPRPIAERM 476
            ::::..|.                ||.::.||:.:|    .....||:.:.|||.::|..:||::
Zfish   804 IKVLLRKNNCGYGSNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQL 868

  Fly   477 RLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVG 541
            :..|....::|:.|::.|.:::..  ..|::....|:.|..||.:::..|..|.:..||||||:|
Zfish   869 KRGEMVQAEAFDSVTIYFSDIVGF--TALSAESTPMEVVTLLNDLYTCFDAIIDNFDVYKVETIG 931

  Fly   542 MVYMAVSGAPDVN-PLHAEHACDLALRVMK-----KFKAHDMGDVAIRVGINSGPVVAGVVGQKV 600
            ..||.|||.|..| .|||.....::|.:::     :.:......:.:|:||:||||.|||||.|:
Zfish   932 DAYMVVSGLPVRNGKLHAREIARMSLALLEAVHSFRIRHRPNLQLRLRIGIHSGPVCAGVVGLKM 996

  Fly   601 PRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVG-YKVESRGTVQVKGKGDMETYWLL 662
            ||||||||||||||||||:.:..||.:|:.|...:::.. :::|.||.|::||||.|.|||||
Zfish   997 PRYCLFGDTVNTASRMESNGEALKIHVSEATRAVLQEFNCFQLELRGDVEMKGKGRMRTYWLL 1059

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DaNP_001036718.1 HNOB 2..161 CDD:285002
HNOBA 218..476 CDD:285003 58/258 (22%)
CYCc 457..643 CDD:214485 72/192 (38%)
Guanylate_cyc 485..662 CDD:278633 75/183 (41%)
npr1aNP_001038402.1 PBP1_NPR_A 48..449 CDD:107380
ANF_receptor 66..421 CDD:279440
PK_GC-A_B 540..814 CDD:270944 45/204 (22%)
TyrKc 554..808 CDD:197581 44/198 (22%)
HNOBA <823..868 CDD:285003 13/44 (30%)
CYCc 847..1032 CDD:214485 72/186 (39%)
Guanylate_cyc 874..1060 CDD:278633 77/188 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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