DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Da and si:ch211-132f19.7

DIOPT Version :9

Sequence 1:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	XP_688903.4	Gene:	si:ch211-132f19.7 / 560410	ZFINID:	ZDB-GENE-130530-619	Length:	1183	Species:	Danio rerio

Alignment Length:	267	Identity:	84/267 - (31%)
Similarity:	141/267 - (52%)	Gaps:	35/267 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 SRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDE-LLYSMIPRPIA----ERMR 477
            ||:|     :..|:|:.::..  |...|:|...||     |:.:| |||:::|..:|    ||.|
Zfish   875 SRQL-----ETTSRLDFLWRL--QARQEVEDMKEL-----REHNECLLYNILPAHVARHFLERDR 927

  Fly   478 LSEEQVCQSFEEVSVIFLEV--MNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPF---VYKV 537
            .:|:...:|:|.|.|:|..:  .:.|.|....|...::.:..||::.:..||.:..|:   :.|:
Zfish   928 NNEDLFSESYERVGVMFASIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELLDEPYFQDIEKI 992

  Fly   538 ETVGMVYMAVSG-APDVNPLHAE--HACDLAL------RVMKKFKAHDMGDVAIRVGINSGPVVA 593
            :|:|..|||.|| :|:......|  |...|.|      ..:|:.......|..:||||:.|||||
Zfish   993 KTIGSCYMAASGLSPEKQECEDEWAHLSTLVLFALAMQETLKEINKRTSNDFWLRVGISHGPVVA 1057

  Fly   594 GVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVKG----KG 654
            ||:|...|:|.::|.|||.||||:|:....:||:.:.|...:.:.|:.::.||.:.|||    :|
Zfish  1058 GVIGATKPQYDIWGMTVNLASRMDSTGLSGRIQVPEATSRVLAEHGFMLQLRGEIYVKGVSERRG 1122

  Fly   655 DMETYWL 661
            .:.||::
Zfish  1123 AVRTYFV 1129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	18/62 (29%)
		CYCc	457..643	CDD:214485	66/204 (32%)
		Guanylate_cyc	485..662	CDD:278633	63/195 (32%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831
		CYCc	338..537	CDD:214485
		Guanylate_cyc	381..559	CDD:278633
		DUF1053	579..667	CDD:283888
		CYCc	903..1103	CDD:214485	65/199 (33%)
		Guanylate_cyc	932..1131	CDD:278633	63/198 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810