Protein Alignment Gyc89Da and npr1b

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_009290669.2
• Gene: npr1b / 555911
• ZFINID: ZDB-GENE-100805-4
• Length: 1070
• Species: Danio rerio
• Alignment Length: 620
• Identity: 170/620 - (27%)
• Similarity: 262/620 - (42%)
• Gaps: 144/620 - (23%)

  Fly   130 VILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQN-----DISGGTAGPIKLTDGPLTVI 189
            |.:||..:  :.|.|:.|:..::.:...:......:.|..     .:.|...|.:..|||...|.
Zfish   501 VFIYRKLK--LEKELVAQLWRISWDDIQMSHLEKALRSTGSKLTLSLRGSNYGSLLTTDGNFQVF 563

  Fly   190 VK--YRLDFDNREYMAKRVNTEAHPSQLKMPTVKLDVFLDLFPFTFVLNH--DMKITHAGEKIVE 250
            .|  |   |.......|.:|........|:              .|.|.|  |::..|....|
Zfish   564 AKTGY---FKGNIVAIKYINRRRVELTRKV--------------LFELKHMRDVQNEHLTRFI-- 609

  Fly   251 TWIMHNPGA---NPKSFIGTHVMDLFQCRRPK--------DTTIDW-------DTLIQMRAVLFE 297
                   ||   .|...|.|.     .|.|..        ..|:||       ..:::..|.|..
Zfish   610 -------GACIDPPNICIVTE-----YCPRGSLQNILENDSITLDWMFKYSLISDIVKGMAFLHN 662

  Fly   298 FELIRTGHNRAAYDAVLN---MDFENY------DEMDLNEAQTMALAK---AQEFSESHPVDDDE 350
            ..::..|:.:::...|.|   :...:|      .|.|..:|.:....|   |.|.|..
Zfish   663 SVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIRTESDTEDAHSYYARKLWLAPELSRM------- 720

  Fly   351 SAREDEIDPATGERRS---SQG--LRSILLKGQMFYIKDVDSLIFLCSPLIENLDELH-GIGLYL 409
                 |..|..|.::.   |.|  |:.:.|:..:||::.     .|.||. |.:|.:. |...||
Zfish   721 -----ECFPPGGTQKGDVYSFGIILQEVALRRGVFYLEG-----DLLSPK-EIVDRVALGEWPYL 774

  Fly   410 N-DLNPHGLSRELVMAGWQHC-----------SKLEIMFEKE--EQRSDELEKSLELADSW---- 456
            . .|||...|.||... .|.|           |.:.::..|:  |.||:.|:..|...:.:
Zfish   775 RPSLNPQAHSEELGQL-MQRCWAEEPSDRPEFSHISVLLRKQNREHRSNILDNLLSRMEQYANNL 838

  Fly   457 --------------KRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNS 507
                          ||:.:.|||.::|..:||:::..|....::|:.|::.|.:::     |..|
Zfish   839 EELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIV-----GFTS 898

  Fly   508 IQG---AMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRV 568
            :..   .:|.|..||.:::..|..|.:..||||||:|..||.|||.|..| .||......::|.:
Zfish   899 LSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLAL 963

  Fly   569 M---KKFKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLS 628
            :   |.||.....|  :.:|:||:||||.|||||.|:||||||||||||:|||||:.:|.||.:|
Zfish   964 LEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVS 1028

  Fly   629 KYTGDKVRQVG-YKVESRGTVQVKGKGDMETYWLL 662
            ..|...:::.. :::|.||.|::||||.|.|||||
Zfish  1029 SATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLL 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	6/30 (20%)
		HNOBA	218..476	CDD:462234	69/327 (21%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	79/186 (42%)
npr1b	XP_009290669.2	Periplasmic_Binding_Protein_type1	50..453	CDD:471960
		PK_GC-A_B	544..818	CDD:270944	68/323 (21%)
		HNOBA	<818..872	CDD:462234	13/53 (25%)
		CYCc	851..1036	CDD:214485	76/189 (40%)