Protein Alignment Gyc89Da and gucy1a1

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 625
• Identity: 157/625 - (25%)
• Similarity: 269/625 - (43%)
• Gaps: 136/625 - (21%)

  Fly    38 THQIYPDKLMPDIAEALSACTGESFD-----FCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFL 97
            :|.:...:.:.|:.:..|..||...|     ..:..|..|    :...|:  ::|..|....|||
Zfish   107 SHTLDNAEQLSDVMKNYSLKTGIPMDALKISLGLEVFRDC----YEEDGH--ILRVVGGALHDFL 165

  Fly    98 QSIDNIHLIMRFTYPKMKSPSMQLTNMDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKA 162
            .|   .:::::.:.|    |:.::.......:::........::.|....:......|.|: |:|
Zfish   166 NS---FNVLLKQSTP----PTPEIQRYIHQASILCLDKDPGLLTVYFFNPLPSTELFFSGI-IQA 222

  Fly   163 YV-------IESQNDISGGTAGPIKLTDGP---LTVIVKYRLDFDNREYMAKRVNTEAHPSQLKM 217
            ..       :|.:.|:.|..:|.::....|   .:|:|:     |.|...         ||.::.
Zfish   223 AACLLYCTRVEVRMDVGGKDSGALQADHQPHLLYSVVVR-----DGRSLT---------PSPMRT 273

  Fly   218 PT---VKLDVFLDLFPFTFVLNHDMKITHAGEKIVETWIMHNPGANPKSFIGTHVMDLFQCRRPK 279
            .|   :.|.:....|||..:|:.:|.:...|:.:...                    |.:||..
Zfish   274 HTSGDIPLSLLYSTFPFHILLDQEMGLLQIGDGLRRR--------------------LGRCRDG- 317

  Fly   280 DTTIDWDTLIQMRAVLFEFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESH 344
                      |.|....|...|.:...||::..:|.|         ||   |..|.:.::...|.
Zfish   318 ----------QRRPAFNEHFAIVSPEIRASFQDILTM---------LN---TQFLLRVKQHGASS 360

  Fly   345 PVDDDESAREDEIDPATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYL 409
            .  |......|                   |||||.::.::.:|:||.||.::.|:||.|.||||
Zfish   361 A--DSPGKHMD-------------------LKGQMIFMSEMSALLFLGSPCVDKLEELTGRGLYL 404

  Fly   410 NDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSD-ELEKSLELADSWKRQGDELLYSMIPRPIA 473
            :|:..|...|::|:.|.|  :|.:...:|...::. .||::.:..:..||:..|||:::.|..:|
Zfish   405 SDIPIHNALRDVVLVGEQ--TKAQDGLKKRLGKAKAALEQAHQALEEEKRRTVELLFTIFPGNVA 467

  Fly   474 ERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQG---AMQTVNTLNKVFSALDEEIISPFVY 535
            :|:........:.|:.|:|:|.:::     |..:|..   .||.||.|:::::..|.......||
Zfish   468 QRLWQGLPVQAKKFDHVTVLFSDIV-----GFTAICSRCTPMQVVNMLSELYTRFDHHCGELDVY 527

  Fly   536 KVETVGMVYMAVSGAPDVNPLHAE---HACDLALRVMKKFKAHD-----MGDV-AIRVGINSGPV 591
            ||||:|..|....|      ||.|   ||..:||..:|..:..|     ||:| .:|:||:||.|
Zfish   528 KVETIGDAYCVAGG------LHKESPTHAVQIALMALKMMELSDEVTTPMGEVIRMRIGIHSGSV 586

  Fly   592 VAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYT 631
            :|||||.|:|||||||:.|..|::.||.|.|.||.:|..|
Zfish   587 LAGVVGVKMPRYCLFGNNVTLANKFESCSLPRKINVSPTT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	20/127 (16%)
		HNOBA	218..476	CDD:285003	61/261 (23%)
		CYCc	457..643	CDD:214485	70/187 (37%)
		Guanylate_cyc	485..662	CDD:278633	62/159 (39%)
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003	60/256 (23%)
		CYCc	449..635	CDD:214485	70/189 (37%)
		Guanylate_cyc	476..647	CDD:278633	62/162 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820