DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gyc89Da and Adcy4

DIOPT Version :9

Sequence 1:NP_001036718.1 Gene:Gyc89Da / 42001 FlyBaseID:FBgn0038435 Length:667 Species:Drosophila melanogaster
Sequence 2:NP_062158.2 Gene:Adcy4 / 54223 RGDID:2034 Length:1072 Species:Rattus norvegicus


Alignment Length:270 Identity:82/270 - (30%)
Similarity:139/270 - (51%) Gaps:53/270 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   427 QHCSKLEIMFEK----EEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERM----RLSEEQV 483
            ::..:|:.:::|    |.:.::.:|....|          ||.:::|..:|.:.    |.:|:..
  Rat   808 EYYCRLDFLWKKKLRQEREETETMENLTRL----------LLENVLPAHVAPQFIGQNRRNEDLY 862

  Fly   484 CQSFEEVSVIFLEV---------MNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISP---FVYK 536
            .||:|.|.|:|..:         .|:..|||       :.:..||::.:..||.:..|   .|.|
  Rat   863 HQSYECVCVLFASIPDFKEFYSESNINHEGL-------ECLRLLNEIIADFDELLSKPKFSGVEK 920

  Fly   537 VETVGMVYMAVSGAPDVNP-----LHAEHAC-------DLALRVMKK---FKAHDMGDVAIRVGI 586
            ::|:|..|||.:|. :..|     ..||.:|       :.|:.:..|   ...|...:..:|||:
  Rat   921 IKTIGSTYMAATGL-NATPGQDTQQDAERSCSHLGTMVEFAVALGSKLGVINKHSFNNFRLRVGL 984

  Fly   587 NSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVK 651
            |.|||||||:|.:.|:|.::|:|||.||||||:....|||:::.|...::.:||...|||.::||
  Rat   985 NHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQSLGYTCYSRGVIKVK 1049

  Fly   652 GKGDMETYWL 661
            |||.:.||:|
  Rat  1050 GKGQLCTYFL 1059

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DaNP_001036718.1 HNOB 2..161 CDD:285002
HNOBA 218..476 CDD:285003 9/52 (17%)
CYCc 457..643 CDD:214485 66/216 (31%)
Guanylate_cyc 485..662 CDD:278633 71/204 (35%)
Adcy4NP_062158.2 AC_N <115..246 CDD:292831
CYCc 219..422 CDD:214485
Guanylate_cyc 264..430 CDD:278633
DUF1053 479..580 CDD:283888
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 498..523
CYCc 824..1039 CDD:214485 68/232 (29%)
Guanylate_cyc 861..1060 CDD:278633 71/207 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.