DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Da and ACXB

DIOPT Version :9

Sequence 1:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_620474.2	Gene:	ACXB / 53427	FlyBaseID:	FBgn0040509	Length:	1114	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	79/328 - (24%)
Similarity:	145/328 - (44%)	Gaps:	66/328 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   379 MFYIKDVDSLIFLCSPLIENLDEL-----HGIGLYLNDLNPHGLSRELVMAGW--QHCSKLEIMF 436
            ::::|..|..|   |.::.:||.:     |.:|..|..:....::..:|.:.:  :|      .|
  Fly   184 IYFLKSDDEDI---SEVVHDLDTICVDIFHYLGFNLMGIFFRIMNDTMVRSSFLDRH------QF 239

  Fly   437 EKEEQRSDELEKSLELADSWKRQGDE----LLYSMIPRPIA--------ERMRLSEE-------- 481
            .|||.              |.||..:    ||.|::|..||        ||:.|||.
  Fly   240 LKEEM--------------WLRQARQQESMLLDSILPPQIAKPIQQSIKERIMLSETDSDRIVVN 290

  Fly   482 -------QVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVET 539
                   ...|...:||:::.:|:| |.. |.:.....:.|..|:.::...|....:..|.:::.
  Fly   291 ARRTENFMAIQIHPDVSILYADVVN-YTH-LTTTLTVEKLVKVLHDLYGRFDMAASTFKVQRIKF 353

  Fly   540 VGMVYMAVSGAPDVNPLHAEHACDLALRV---MKKFKAHDMGDVAIRVGINSGPVVAGVVGQKVP 601
            :|..|..|:|..:.:|.||..|..|.:.:   :::.:||...|:.:|:|::||.::|||:||...
  Fly   354 LGDCYYCVAGLGEADPDHARMAVSLGISMIANIQEVRAHRALDIDMRIGVHSGTLLAGVIGQAKL 418

  Fly   602 RYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKV----ESRGTVQVKGKGDMETYWLL 662
            :|.::|..|:.|:|:|::..|..:.:|..|...:....|.|    |...:..:..|..|.||.|.
  Fly   419 QYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPGTEVAQSDPILQKQPMTTYLLT 483

  Fly   663 EGP 665
            ..|
  Fly   484 AAP 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	25/115 (22%)
		CYCc	457..643	CDD:214485	56/219 (26%)
		Guanylate_cyc	485..662	CDD:278633	48/183 (26%)
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	24/114 (21%)
		CYCc	249..459	CDD:214485	53/211 (25%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	49/187 (26%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740