DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc89Da and ACXE

DIOPT Version :9

Sequence 1:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_652601.3	Gene:	ACXE / 53426	FlyBaseID:	FBgn0040506	Length:	1123	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	74/298 - (24%)
Similarity:	129/298 - (43%)	Gaps:	80/298 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   429 CSKLEIMFEKEEQRSDELEKSLELADSWK---RQGDE-----------LLYSMIPRPIAE---RM 476
            |....|||.||.|    :|.:.::..:|:   |:.:.           :|.:::|..|.:   ..
  Fly   785 CITFLIMFVKERQ----IEFTNKVNFNWRVDLRKEENAASLTNHSIIIILNNILPSHIVDVYLNS 845

  Fly   477 RLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVY----KV 537
            ....|...:::..|||:|..::| ::..|.|::       .||::.:..|..::....|    |:
  Fly   846 LAKHELYFENYRMVSVMFAMLIN-FEMDLRSLR-------VLNEIIAEFDTLLLFYKEYYTVEKI 902

  Fly   538 ETVGMVYMAVSGAPDVN--------------P-------------------------LHAEHACD 563
            :.||..|||..|. |:|              |                         :...:|.|
  Fly   903 KIVGCTYMAACGL-DLNFAGSTSTNRKESIPPTEFNEEQSRRILFQQSNEDLDEVVFVMTSYALD 966

  Fly   564 LALRVMKKFKAH-------DMGDVAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSD 621
            :...:.|..:|:       ::.|..|.:||:||.|:||:||...|.|.::|:.||.||||||:..
  Fly   967 MMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVMAGIVGASQPHYDIWGNPVNMASRMESTGL 1031

  Fly   622 PWKIQLSKYTGDKVRQVGYKVESRGTVQVKGKGDMETY 659
            |..|.:::.|.:.::|.|.....||...|||:|.:.||
  Fly  1032 PGHIHVTEETSEILQQFGITCSYRGMTFVKGRGKIPTY 1069

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	13/63 (21%)
		CYCc	457..643	CDD:214485	57/252 (23%)
		Guanylate_cyc	485..662	CDD:278633	60/225 (27%)
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454
		Nucleotidyl_cyc_III	290..459	CDD:325147
		Nucleotidyl_cyc_III	851..1071	CDD:325147	60/228 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740