DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gyc89Da and Ac76E

DIOPT Version :9

Sequence 1:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001246838.1	Gene:	Ac76E / 40180	FlyBaseID:	FBgn0004852	Length:	1312	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	86/352 - (24%)
Similarity:	160/352 - (45%)	Gaps:	79/352 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 SSQGLRSILLKGQMFYIKDVDSLIFLCSPL----IENLDELHGIGLYLNDLN-PHGLSRELVMAG 425
            |...:.:.|..|  |.:|.:..|:.:.:.:    ..:|.|::      ||.| .|||..|:  .|
  Fly   976 SLAAISAFLRSG--FILKLIAMLVAVIAQVTVLGYSDLFEMY------NDANITHGLPLEI--KG 1030

  Fly   426 W-----------------QHCSKLEIMFE---KEEQRSDELEKSLELADSWKRQGDELLYSMIPR 470
            :                 ::.::.:.:::   |.||...|..:.:...         ||.:::|.
  Fly  1031 FLLLLVIILVLHTLDRQGEYVARTDFLWKAKLKVEQEEVETMRGINKI---------LLENILPA 1086

  Fly   471 PIAE---RMRLSEEQVCQSFEEVSVIFLEVMN---VYDEGLNSIQGAMQTVNTLNKVFSALDEEI 529
            .:|.   .:..|.|...:|:..|:|:|..:.|   .|||...:.|| ::.:..||::....|:.:
  Fly  1087 HVATHFLHLERSTELYHESYSCVAVMFASIPNYKEFYDETDVNKQG-LECLRLLNEIICDFDKLL 1150

  Fly   530 ISP---FVYKVETVGMVYMAVSGAPDVNPLHAEHACDLALRVMKKFKAHD---MGDVAI------ 582
            :.|   .:.|::|:...||..||   :.|...:.|...:....|:.:.|:   :.:.||
  Fly  1151 LKPKFSGIEKIKTIASTYMCASG---LRPGKEDGATSRSFADEKRTEEHNVVILVEFAIALMSIL 1212

  Fly   583 -------------RVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDK 634
                         |:|:|.|||:|||:|.:.|:|.::.:|||.||||:|.....::|.::.|...
  Fly  1213 DSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMGRLQTTENTAKI 1277

  Fly   635 VRQVGYKVESRGTVQVKGKGDMETYWL 661
            :...||:.|.||...|||||::.||::
  Fly  1278 LMTAGYECECRGLTYVKGKGNLVTYFV 1304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	24/137 (18%)
		CYCc	457..643	CDD:214485	56/216 (26%)
		Guanylate_cyc	485..662	CDD:278633	60/205 (29%)
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831
		CYCc	259..467	CDD:214485
		Guanylate_cyc	311..469	CDD:278633
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485	54/207 (26%)
		Guanylate_cyc	1101..1305	CDD:278633	60/208 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740