DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Da and GUCY2F

DIOPT Version :9

Sequence 1:NP_001036718.1 Gene:Gyc89Da / 42001 FlyBaseID:FBgn0038435 Length:667 Species:Drosophila melanogaster
Sequence 2:NP_001513.2 Gene:GUCY2F / 2986 HGNCID:4691 Length:1108 Species:Homo sapiens


Alignment Length:249 Identity:96/249 - (38%)
Similarity:151/249 - (60%) Gaps:21/249 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   427 QHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVS 491
            |:.|.||.:.   .:|::|||  :|     |::.::||..|:|..:||.::.......:.|:.|:
Human   830 QYSSNLEDLI---RERTEELE--IE-----KQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVT 884

  Fly   492 VIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-P 555
            :.|.:::..  ..::::...::.|:.||.:::..|..|.|..||||||:|..||..||.|..| .
Human   885 LYFSDIVGF--TTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGS 947

  Fly   556 LHAEHACDLALRVMKK---FKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASR 615
            .||....:::|.::..   ||...|.:  |.||:|::||||||||||..:|||||||||||||||
Human   948 RHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASR 1012

  Fly   616 MESSSDPWKIQLSKYTGDKVRQV--GYKVESRGTVQVKGKGDMETYWLLEGPEG 667
            |||:..|::|.:|..|...::.:  ||:||.||..::||||..||:||: |.:|
Human  1013 MESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLI-GKKG 1065

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DaNP_001036718.1 HNOB 2..161 CDD:285002
HNOBA 218..476 CDD:285003 16/48 (33%)
CYCc 457..643 CDD:214485 73/193 (38%)
Guanylate_cyc 485..662 CDD:278633 77/184 (42%)
GUCY2FNP_001513.2 PBP1_sensory_GC_DEF_like 54..435 CDD:107366
ANF_receptor 75..412 CDD:279440
PKc_like 545..815 CDD:304357
HNOBA <824..869 CDD:285003 16/48 (33%)
CYCc 848..1040 CDD:214485 73/198 (37%)
Guanylate_cyc 875..1062 CDD:278633 78/189 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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