Protein Alignment Gyc89Da and GUCY2F

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001513.2
• Gene: GUCY2F / 2986
• HGNCID: 4691
• Length: 1108
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 96/249 - (38%)
• Similarity: 151/249 - (60%)
• Gaps: 21/249 - (8%)

  Fly   427 QHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVS 491
            |:.|.||.:.   .:|::|||  :|     |::.::||..|:|..:||.::.......:.|:.|:
Human   830 QYSSNLEDLI---RERTEELE--IE-----KQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVT 884

  Fly   492 VIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-P 555
            :.|.:::..  ..::::...::.|:.||.:::..|..|.|..||||||:|..||..||.|..| .
Human   885 LYFSDIVGF--TTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGS 947

  Fly   556 LHAEHACDLALRVMKK---FKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASR 615
            .||....:::|.::..   ||...|.:  |.||:|::||||||||||..:|||||||||||||||
Human   948 RHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASR 1012

  Fly   616 MESSSDPWKIQLSKYTGDKVRQV--GYKVESRGTVQVKGKGDMETYWLLEGPEG 667
            |||:..|::|.:|..|...::.:  ||:||.||..::||||..||:||: |.:|
Human  1013 MESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLI-GKKG 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233
		HNOBA	218..476	CDD:462234	16/48 (33%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	77/184 (42%)
GUCY2F	NP_001513.2	PBP1_sensory_GC_DEF-like	54..435	CDD:380594
		Protein Kinases, catalytic domain	545..815	CDD:473864
		HNOBA	<824..869	CDD:462234	16/48 (33%)
		CYCc	848..1040	CDD:214485	73/198 (37%)