Protein Alignment Gyc89Da and Gucy2f

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001007577.1
• Gene: Gucy2f / 245650
• MGIID: 105119
• Length: 1108
• Species: Mus musculus
• Alignment Length: 715
• Identity: 171/715 - (23%)
• Similarity: 283/715 - (39%)
• Gaps: 208/715 - (29%)

  Fly   120 QLTNMDDNGAVILYRSSRTGMSKYLI----GQMTEVAREFYGLEIKAYVIE-------------- 166
            ||...|.||         .|:|:|:|    |:..|: |..|.::::..::.
Mouse   392 QLIKTDSNG---------NGISEYVILDTNGKEWEL-RGTYTVDMETELLRFRGTPIHFPGGRPT 446

  Fly   167 --------SQNDISGGTAGP------------------------------IKLTDGPLTVIVKYR 193
                    ::..|..|...|                              |:|..||..:::...
Mouse   447 SADAKCWFAERKICQGGIDPALAMMVCFALLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLE 511

  Fly   194 -LDFDNREYMAKRVNTEAHPSQL-------KMPTVKLDVFLDLFPFTFVLNHDMKITHAGEKIVE 250
             :.|.|..:.:||.:..:...|:       :.|.:..... .|.|.|:. |.::.| :.|:.:
Mouse   512 DVTFINPHFGSKRGSRASVSFQIISEVQSGRSPRLSFSSG-SLTPATYE-NSNIAI-YEGDWV-- 571

  Fly   251 TWIMHNPGANPKSF-----IGTHVMDLFQ-----------------------------CRRPK-- 279
             |:...|   |..|     |.:...|:|:                             |.|..
Mouse   572 -WLKKFP---PGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLE 632

  Fly   280 ------DTTIDWD-------TLIQMRAVLFEFELI--RTGHNRAAYDAVLNMDFENYDEMDLNEA 329
                  |..:||.       .||:....|...|.|  |........|....:...:|...|:.|.
Mouse   633 DILTNDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDILEM 697

  Fly   330 QTMALAKAQEFSESHPVDDDESAREDEIDPATGERR--SSQG--------LRSILLKGQMFYIKD 384
            ..:        ||..|.:::......|:..|.|..|  |..|        ::.::::|..|.:.|
Mouse   698 LRL--------SEEEPSEEELLWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMD 754

  Fly   385 VDSLIFLCSPLIENLDELH-GIGLYLNDLNPHGLSRE---LVMAGWQHCSK-------------- 431
            :        |..|.:|.|. ...:|...::|.....|   |:...|...|:
Mouse   755 L--------PAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKT 811

  Fly   432 ---------LEIMFEKEEQRSDELE-------KSLELADSWKRQGDELLYSMIPRPIAERMRLSE 480
                     ::.|....||.|..||       :.||:.   |::.::||..|:|..:||.::...
Mouse   812 FNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIE---KQKTEKLLTQMLPLSVAESLKKGC 873

  Fly   481 EQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYM 545
            ....:.|:.|::.|.:::..  ..::::...::.|:.||.:::..|..|.|..||||||:|..||
Mouse   874 TVEPEGFDLVTLYFSDIVGF--TTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYM 936

  Fly   546 AVSGAPDVN-PLHAEHACDLALRVMKK---FKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYC 604
            ..||.|..| ..||....:::|.::..   ||...|.:  |.||:|::||||||||||..:||||
Mouse   937 VASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYC 1001

  Fly   605 LFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQV--GYKVESRGTVQVKGKGDMETYWLLEGPEG 667
            ||||||||||||||:..|::|.:|..|...::.:  ||:||.||..::||||..||:||: |.:|
Mouse  1002 LFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLV-GKKG 1065

  Fly   668  667
            Mouse  1066  1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	13/44 (30%)
		HNOBA	218..476	CDD:285003	66/352 (19%)
		CYCc	457..643	CDD:214485	73/193 (38%)
		Guanylate_cyc	485..662	CDD:278633	77/184 (42%)
Gucy2f	NP_001007577.1	PBP1_sensory_GC_DEF-like	54..435	CDD:380594	13/52 (25%)
		PKc_like	545..815	CDD:419665	50/294 (17%)
		HNOBA	<824..869	CDD:400168	15/47 (32%)
		CYCc	848..1040	CDD:214485	72/196 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810