Protein Alignment Gyc89Da and gcy-36

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_510557.3
• Gene: gcy-36 / 191657
• WormBaseID: WBGene00001556
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 702
• Identity: 196/702 - (27%)
• Similarity: 327/702 - (46%)
• Gaps: 118/702 - (16%)

  Fly     1 MYGMLYESVQHYVQEEYGVDIWRKVCHIIDCKHNSFKT------HQIYPDKLMPDIAEALSACTG 59
            |:|.::||::..:...||...|.||     .:...|:.      :..|.|.....:.:|:|....
 Worm     1 MFGFIHESIRQLMIRTYGEAFWSKV-----LERAGFEAGKENIINHYYSDADTFSLVDAVSVILK 60

  Fly    60 ESFDFCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPK--MKSPSMQLT 122
            .:.:.....:|...:::....|:|.:|||.......||.::|::|..:.....|  ::.||.:..
 Worm    61 VTREQVWEMYGCFLIQYTMETGWDDLIRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPSFRCE 125

  Fly   123 NMDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQNDISGGTAGPIKLTDGPLT 187
            :..|....:.|.:.|.|:...:.|.:.|.|:..:.|::..       .|:|.|...:::..|.
 Worm   126 DNPDGTITLHYYTGRPGLYPIVKGVLREAAKRVFKLDVSM-------TITGRTQRSVQMATGE-- 181

  Fly   188 VIVKYRLDFDNREYMAKRVNTE------------AHPSQLKMPTVKLDVFLDLFPFTFVLNHDMK 240
                 |:: ::..::.|.:||:            .|.:..|:....:| |:..||:..|::.|.|
 Worm   182 -----RIE-EHVIFLVKTLNTDQSNEEALGTAVVQHSNNYKIRLTHMD-FISTFPYHMVVDQDCK 239

  Fly   241 ITHAGEKIVETWIMHNPGANPKSF--IGTHVMDLFQCRRPKDTTIDWDTL---------IQMRAV 294
            |...|.::..    |    .||..  :||.:|.:|:..||: ..:|:|::         :|::..
 Worm   240 IVQVGRELYN----H----IPKDLLSVGTPLMRIFEVTRPQ-IPLDFDSICNFINAVFVLQVKTT 295

  Fly   295 LFEFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDDDESAREDEIDP 359
            ..||:  |..:.|||.....:   ||     |.|....|||.:|
 Worm   296 PMEFQ--RNANKRAAQAIEAS---EN-----LYEDNNGALALSQ--------------------- 329

  Fly   360 ATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMA 424
                   ||.|:   |||||..:.....:::||||.:.::.||...||.|..:..|..:|:|::.
 Worm   330 -------SQHLK---LKGQMMLMSSGGHIMYLCSPYVTSIPELLQYGLRLTAMPIHDPTRDLILL 384

  Fly   425 GWQHCSKLE--IMFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSF 487
            ..|..|.:|  :..|...::.:.:.|.||:.   |.:.|.||..|:|..:|::::.......:.:
 Worm   385 NQQRLSDVEMNLQLEANNEQLENMAKDLEVE---KGKTDALLREMLPPSVAQQLKQGLSVEAREY 446

  Fly   488 EEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPD 552
            ||.:|:|.:|...  :.:..:......|:.||::|:..|..|.....|||||||..||:|.|.||
 Worm   447 EEATVMFTDVPTF--QQIVPLCTPKDIVHLLNELFTKFDRLIGIQKAYKVETVGDSYMSVGGIPD 509

  Fly   553 VNPLHAEHACDLALRVMKKFKAHDMGD------VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVN 611
            :...|.|..|.|||.::  .:|..:.|      :.||.||:||||||||||.|:|||||||||||
 Worm   510 LVDDHCEVICHLALGMV--MEARTVCDPITNTPLHIRAGIHSGPVVAGVVGAKMPRYCLFGDTVN 572

  Fly   612 TASRMESSSDPWKIQLSKYTGDKVRQVG-YKVESRGTVQVKGKGDMETYWLL 662
            |:|||||.|...:|..|:.........| ::.|.||.||:||||:|.||:||
 Worm   573 TSSRMESHSPIGRIHCSENAKKCAESTGRFEFEPRGRVQIKGKGEMNTYFLL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	34/166 (20%)
		HNOBA	218..476	CDD:285003	69/270 (26%)
		CYCc	457..643	CDD:214485	75/192 (39%)
		Guanylate_cyc	485..662	CDD:278633	80/183 (44%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:285002	34/175 (19%)
		HNOBA	217..435	CDD:285003	69/271 (25%)
		CYCc	415..604	CDD:214485	75/195 (38%)
		Guanylate_cyc	441..624	CDD:278633	80/186 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4189
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.730