Protein Alignment Gyc89Da and gcy-19

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001348702.1
• Gene: gcy-19 / 191650
• WormBaseID: WBGene00001544
• Length: 1187
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 151/571 - (26%)
• Similarity: 227/571 - (39%)
• Gaps: 140/571 - (24%)

  Fly   181 LTDGPLTVIVKYRLDFDNR------EYMAKR-VNTEAHPSQLKMPTVKLDVFLDLFPFTFVLNHD 238
            |..||..:....::.|||.      .|:.|. |.:.|||:...:.| ..|.|:.|
 Worm   573 LQSGPSNITDTSKMTFDNTFSNYSIFYLDKEPVLSTAHPASNLIRT-DYDTFVRL---------- 626

  Fly   239 MKITHAGEKIVETWIMHNPGANPKSFIGTHVMDLFQCRRPKDTTIDWDTLIQMRAVL-------- 295
            .|:.|               .|...|:|..:      ..|:...: |.  :.||..|
 Worm   627 RKLDH---------------ENVNKFVGMSI------DGPEYLAV-WK--LCMRGSLQDIIGQGN 667

  Fly   296 ------FEFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDDDESARE 354
                  |.|.:||        |....:.:.:...:.::...........|..::...|.......
 Worm   668 FSIDPFFMFCVIR--------DMAEGLKYLHNSFLHVHANLRSGTVLVNESWQAKLTDFGLGTLA 724

  Fly   355 DEIDPATGERR----SSQGLRSILLKGQMFYIKDVDSLIFLCSPLI---------ENLDELHGIG 406
            :|..|.  :||    :.:.:|..||..|:....|:.||..:.|.::         |..|.:..|.
 Worm   725 EEKKPM--KRRQLWMAPEVIRGTLLPHQIEKSADIYSLAVIASEVLTRKEAWNMAERKDTVDEIV 787

  Fly   407 LYLNDLNPHGLSRELVMAG--------------WQH-----------CSKLEIMFEKEEQRSD-- 444
            ..:....|:....||.|.|              |..           |:.|:.|..|:....|
 Worm   788 YRIKKGGPNAPRPELDMDGVEINHNLLILIRDCWSEEPADRPSADVICNLLKNMMPKKGNLMDHV 852

  Fly   445 -------------ELEKSLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLE 496
                         |:|...:...:.|::.|.||..|:|:.:|||::..:....:.|:.|:|.|.:
 Worm   853 FNILEDYTTNLEVEVEDRTKELTAEKKKADVLLGRMLPKQVAERLKQGQTVEPEGFDSVTVFFSD 917

  Fly   497 VMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEH 560
            |:....  |.:.....|.||.||.::|..|..|.....||||::|..|:.|||.|..| ..|.:.
 Worm   918 VVKFTQ--LAAKCSPFQVVNLLNDLYSNFDAIIEEHGCYKVESIGDGYLCVSGLPSKNGNAHIKQ 980

  Fly   561 ACDLALRVM---KKFKAHDM--GDVAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSS 620
            ..:|:|..|   |.||...:  ..|.:|:|:||||.||||||..:||||||||||||||||||:.
 Worm   981 IVELSLDFMSYCKSFKIPHLPREKVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNG 1045

  Fly   621 DPWKIQLS--------KYTGDKVRQVGYKVESRGTVQVKGKGDMETYWLLE 663
            ....|.||        |:..::     |...|||.|.:||||.|||:|:.|
 Worm  1046 KASHIHLSAASYTLLMKHYPNQ-----YNTASRGDVIIKGKGVMETFWVFE 1091

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233
		HNOBA	218..476	CDD:462234	57/324 (18%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	80/190 (42%)
gcy-19	NP_001348702.1	PBP1_NPR_GC-like	45..466	CDD:380575
		Protein Kinases, catalytic domain	571..841	CDD:473864	56/312 (18%)
		CYCc	876..1065	CDD:214485	76/190 (40%)