Protein Alignment Gyc89Da and gcy-14

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_506660.2
• Gene: gcy-14 / 191647
• WormBaseID: WBGene00001540
• Length: 1111
• Species: Caenorhabditis elegans
• Alignment Length: 834
• Identity: 198/834 - (23%)
• Similarity: 320/834 - (38%)
• Gaps: 257/834 - (30%)

  Fly    13 VQEEYGVDIWRKVCHIIDCKHNSFKTHQIYPDKLMPDIA----EALSACTGESFDF---CMN--- 67
            :::.||     ||.:|.|        :...|..:.|:.|    :.:|..|.:.|:.   |.|
 Worm   292 IRDAYG-----KVLYICD--------NMGLPTTITPEFANFSSQLISRMTEQPFNCVQDCSNSTY 343

  Fly    68 -----FFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPKMKSPSMQLTN---- 123
                 :.|:.|..|::   |...:               |..|....|...:|:.|..|::
 Worm   344 KVPATYAGQLFDAFYA---YGVAL---------------NRSLTQDPTRANLKNGSFVLSDIGMS 390

  Fly   124 ----------MDDNGA--VILYR-SSRTGMSKYLIGQM----TEV------------------AR 153
                      :||.|.  |.:|. :..|.:..||...:    :||                  ||
 Worm   391 FQGVGGGTVTLDDTGTRIVQVYMFALNTSLLPYLAASLVINGSEVEYTPFYKSEADLWSVRPLAR 455

  Fly   154 E---FYGLE-----IKAYVIES-------QNDISGGTAGPIKLTDGPLTVIVK----------YR 193
            .   |.|||     :|.|::.:       ...:..|.||.:      .|:.:|          ::
 Worm   456 PICGFSGLECPPDFVKEYLVYTIIAAVIVVLALLAGCAGLL------YTMQMKRKEMERQDLLWQ 514

  Fly   194 LDFDNREYMAKRVNTEAH-------PSQLKMPTVKLDVFLDLFPFTF-------VLNHDMKITHA 244
            :.|...:.:..:...||.       ||.....||:.......|.|.:       .:.||:.:...
 Worm   515 VPFIELQQVQSKSKAEASMHSFASGPSTSTKITVESRSETINFIFYYYQQDILAAMKHDLILQFD 579

  Fly   245 GEKIVETWIMHN-PGANPKSFI-----GTHVMDLFQ-CRRPKDTTIDWDTLIQMRAVLFEFELIR 302
            .|:..|...|.| ...|...||     |..:..|:: |.|...:.:...:.:||.: .|.|.|||
 Worm   580 AEQKAEFRQMRNFDNDNLNKFIGLCLDGPQLFSLWRFCSRGSLSDVISKSSMQMDS-FFMFSLIR 643

  Fly   303 T----------------GH--NRAA-YDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDD 348
            .                ||  :|.. .|....:....|   .|...:|....|.::...:.|
 Worm   644 DISNGLLFIHNSFLKCHGHLTSRCCLIDDRWQIKISGY---GLKSVRTFENPKKEDLLWTPP--- 702

  Fly   349 DESAREDEIDPATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPL--------IENLDELHGI 405
             |:.|.:      .|.|..:|              |:.|...:||.:        :||..|...:
 Worm   703 -ENLRNE------NEERLPEG--------------DIYSFGIICSEILTRSSAFDLENRKEKPDV 746

  Fly   406 GLY------------------LNDLNPHGLSRELVMAGW-----------------------QHC 429
            .:|                  ..::||..|  .|:...|                       :..
 Worm   747 IIYQVKKGGHNPMRPSLDTGETVEINPALL--HLIRDCWTERPSERPSIEQVRGHLNGMRDGRKS 809

  Fly   430 SKLEIMFEKEEQRSDELEKSL-----ELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEE 489
            :.::.:|...|..:..||:.:     ||.:. |::.|.|||.|:|:.:|::::|.:....::||:
 Worm   810 NLMDHVFNMLETYASTLEEEVSDRTKELVEE-KKKSDVLLYRMLPKMVADKLKLGQTVEPETFEQ 873

  Fly   490 VSVIFLEVMNVYDEGLNSIQG---AMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAP 551
            |::.|.:|:.     ..::.|   .:|.|..||.:::..|..|....||||||:|..|:.|||.|
 Worm   874 VTIFFSDVVQ-----FTTLAGKCTPLQVVTLLNDLYTIFDGIIEQNDVYKVETIGDGYLCVSGLP 933

  Fly   552 DVN-PLHAEHACDLALRVMKK---FKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTV 610
            ..| ..|..|...::|..:..   |:...:..  :.:|:|||.|.|||||||..:||||||||.|
 Worm   934 HRNGNEHIRHIARMSLGFLSSLEFFRVQHLPSERINLRIGINCGSVVAGVVGLTMPRYCLFGDAV 998

  Fly   611 NTASRMESSSDPWKIQLSKYTGDKVRQV--GYKVESRGTVQVKGKGDMETYWLL 662
            ||||||||:..|.||.::......:.||  |::.||||.|.:||||.|||||||
 Worm   999 NTASRMESNGKPGKIHVTAEANQMLTQVVGGFRTESRGEVIIKGKGVMETYWLL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	40/209 (19%)
		HNOBA	218..476	CDD:462234	65/344 (19%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	78/187 (42%)
gcy-14	NP_506660.2	PBP1_NPR_GC-like	21..419	CDD:380575	29/157 (18%)
		Protein Kinases, catalytic domain	535..800	CDD:473864	53/294 (18%)
		HNOBA	<816..860	CDD:462234	14/44 (32%)
		CYCc	839..1031	CDD:214485	73/197 (37%)