Protein Alignment Gyc89Da and gcy-11

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001359843.1
• Gene: gcy-11 / 181745
• WormBaseID: WBGene00001537
• Length: 1168
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 157/666 - (23%)
• Similarity: 261/666 - (39%)
• Gaps: 214/666 - (32%)

  Fly   119 MQLTNMDDNGAVILYRSSRTG---------MSKYL-IGQMTEVAREFYGLEIKAYVIESQNDISG 173
            :||.:|...|      |||.|         .|:|. .|.:......||...|:...|. :|.:..
 Worm   560 VQLVDMTKFG------SSRGGSMIQSAMSMRSQYEDSGPVGGATMNFYTNGIRKAAIR-RNQMQR 617

  Fly   174 GTAGPIKLTDGPLTVIVKYRLDFDNREYMAKRVNTEAHPSQLKMPTVKLDVFLDLFP-------- 230
            ...||....|..|.::..:...::|.....:::|    .:|||: |.::...:||..
 Worm   618 SDKGPAANRDEWLEIVDWHLAKYENTLVTVRKIN----KTQLKL-TREMKQEIDLLMNETHENLN 677

  Fly   231 --FTFVLNHDMKITHAGEKIVETWIMHNPGANPKSFIGTHVMDLFQCRRPKDTTIDWDTLIQMRA 293
              |..:...|:..|           :|:.|  |:.    .:|||.   |..|..:|     :|..
 Worm   678 RFFGLINESDLIFT-----------IHSYG--PRK----SLMDLL---RNDDLRLD-----RMFK 717

  Fly   294 VLFEFELI----------RTGH------NRAAYDAVLNMDFENY--DEMDLNEAQT--------- 331
            |.|..:::          :.|:      :....||...:...||  :::.:.|.::
 Worm   718 VSFVEDVVKGLQFLHEGSKIGYHGNLKSSNCIVDAYWRIKLSNYGMEQIRVEEPESKPDDLLWFA 782

  Fly   332 ---------------MALAKAQEFS----------ESHPVDDDESAREDEI-------------- 357
                           :.||||..:|          ...|..|| ....|||
 Worm   783 PEIIRRYAVKHDLSKLELAKADIYSLAIVLYEIYGRQGPFGDD-LLDSDEIIEQLKFPDGGALTR 846

  Fly   358 -----------------------DPATGERRSSQGLRSIL------LKGQMFYIKDVDSLIFLCS 393
                                   |||:  |.|.:.:|.:|      |||.:     .|:::.|
 Worm   847 PDIHLITKAPYPLASVVEKCWVEDPAS--RPSIKKVRELLKPLSKGLKGNI-----ADNIMNL-- 902

  Fly   394 PLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKR 458
                 ||.      |.|:|.                   :::.|:.||..||           ::
 Worm   903 -----LDR------YRNNLE-------------------DVIKERTEQLEDE-----------RK 926

  Fly   459 QGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFS 523
            :.:.||..::|:.:|..::..:....:.::.||:.|.:::..  ..|:|....:|.||.||.:::
 Worm   927 RNESLLLQLLPKSVANSLKNGQPVDAEFYDSVSIYFSDIVGF--TALSSKSTPLQVVNMLNNLYT 989

  Fly   524 ALDEEIISPF-VYKVETVGMVYMAVSGAPDVNP-LHAEHACDLALRVMKKFKAHDMG-----DVA 581
            ..| .||..| .|||||:|..||.|||.|:||. |||......:|.::...|...:.     .:.
 Worm   990 NFD-TIIDKFDCYKVETIGDAYMFVSGLPEVNSYLHAGEVASASLELLDSIKTFTVSHCPDEKLR 1053

  Fly   582 IRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQV-GYKVESR 645
            :|:|.::||||.||||.::||||||||||..|:.||||.:|.:||:|....:.:.:. ||..|.|
 Worm  1054 LRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYELILKCGGYVTEQR 1118

  Fly   646 GTVQVKGKGDMETYWL 661
            ..:.:|.|.::.|||:
 Worm  1119 EKIVLKNKLEVMTYWM 1134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	13/51 (25%)
		HNOBA	218..476	CDD:285003	61/362 (17%)
		CYCc	457..643	CDD:214485	68/193 (35%)
		Guanylate_cyc	485..662	CDD:278633	71/185 (38%)
gcy-11	NP_001359843.1	Periplasmic_Binding_Protein_type1	<234..452	CDD:385651
		PKc_like	640..890	CDD:389743	47/282 (17%)
		CYCc	923..1116	CDD:214485	70/206 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810