Protein Alignment Gyc89Da and gcy-22

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_508018.2
• Gene: gcy-22 / 180365
• WormBaseID: WBGene00001547
• Length: 1058
• Species: Caenorhabditis elegans
• Alignment Length: 770
• Identity: 183/770 - (23%)
• Similarity: 290/770 - (37%)
• Gaps: 248/770 - (32%)

  Fly   109 FTYPKMKSPSMQLTNMDD--------NGAVILY-----RSSRTGMSKYLIGQMTEVAR--EFYGL 158
            |:.|....|:  .||:|.        ..|::||     ||..||.......:..|||:  ||.|.
 Worm   315 FSRPPFSCPN--CTNIDPTVSQVGPLGDALLLYAYALNRSIATGNPNPTGTEFCEVAKGMEFLGF 377

  Fly   159 EIKAYVIESQNDISGGTAGPIKLTDGPLTVIVKYRLDFDNREYMAKRVNTEAHPSQLKMPTVKLD 223
            ..|  ||.:||.           |..||.|:  |.||..::|.:..::            |..||
 Worm   378 TGK--VIINQNS-----------TRTPLFVV--YNLDSTDKEMIVMQI------------TEDLD 415

  Fly   224 VFLDLFPFTFVLNHDMKITHAGEKIVETW---------IMHNPGAN-PKSFIGTHVMDLFQC--- 275
            ...|  |....:|:.:.:.....:|.:||         |....|.: ||||...::..:..|
 Worm   416 DSKD--PVASSVNYYITLVATPAQIWDTWGGTVPLSTPICGFTGTDCPKSFTDQYLAIILGCTAA 478

  Fly   276 ------------------------------------------------RRPKDTTIDWDTLIQMR 292
                                                            .|...:|:...|.:.:.
 Worm   479 ALVLIIAVISTIVFLVRSKRQEEERLNQLWQVHFSSLVKPPQKNTMHSSRSLQSTVTTSTKVTIN 543

  Fly   293 -------------------AVLFEFELIRTGHNRAAYDAVLNMDFEN---YDEMDLNEAQTMAL- 334
                               |....|....|.::||.:..:.|:|.:|   :..:.|:....:::
 Worm   544 SKKDTERHSFYFLNNDSVVARKHNFRATFTKNDRAMFRKMRNVDNDNLCKFIGLSLDSPTLISIW 608

  Fly   335 -------------------------------AKAQEFSESHPVDDDE--SAREDEIDPATGERRS 366
                                           |.|..:....|:....  |:....:|.....:.|
 Worm   609 RYCSRGSLQDVIAKGSLQMDWFFKYSLMRDVADAIYYLHHSPIGPHGWLSSSTCLVDERWQVKVS 673

  Fly   367 SQGLRSIL---LKGQMFYI-----------------KDVDSLIFLCS------------------ 393
            ..||.:|.   :|.|..::                 .|:.|...:||
 Worm   674 FFGLSAIKQYEVKEQRDFLHTAPEHIRDTNLPITKEMDIYSFAIICSELITKKSAWDLENETFDI 738

  Fly   394 ----------------PLIENLDELHG-IGLYLNDL-------NPHGLSRELVMAGWQHCSKLEI 434
                            |.:|..||.:| :.|.:.|.       .|.....:.:|....|.....:
 Worm   739 EELVYKIKKGGRSPPRPSLETEDEHNGSMSLLVRDCWNENPDQRPTSEQIKTLMKSMNHNRSSNL 803

  Fly   435 M---FEKEEQRSDELEKSL-----ELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVS 491
            |   |...||.:..||..:     ||.:. |::.|.|||.|:|:.:||:::|.:....::|:.|:
 Worm   804 MDHVFNVLEQYASNLEDEVQARMKELTEE-KKRSDVLLYRMLPKQVAEKLKLGQSVEPETFDCVT 867

  Fly   492 VIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPL 556
            :.|.:|::.  ..|.|....:|.||.||.:::..|..|....||||||:|..|:.|||.|..|
 Worm   868 IFFSDVVSF--TTLASRCTPLQVVNLLNDLYTTFDAIIEQHDVYKVETIGDGYLCVSGLPHRN-- 928

  Fly   557 HAEHACDLA------LRVMKKFKAHDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTA 613
            ..|||.:::      |:.:|.|:...:..  :.||||:::||||.||||..:||||||||:||||
 Worm   929 GNEHAKEISSMSFSLLKAIKTFRVPHLPKERINIRVGLHTGPVVTGVVGMTMPRYCLFGDSVNTA 993

  Fly   614 SRMESSSDPWKIQLSKYTGDKVRQV--GYKVESRGTVQVKGKGDMETYWLLEGPE 666
            |||||:..|.::.:|......:.:|  ||:.|.||.|.|||||.::|:|||...|
 Worm   994 SRMESNGKPGRVHISTECMKFLTEVIGGYQTEPRGEVIVKGKGAVQTHWLLTDDE 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	19/66 (29%)
		HNOBA	218..476	CDD:285003	70/444 (16%)
		CYCc	457..643	CDD:214485	76/195 (39%)
		Guanylate_cyc	485..662	CDD:278633	77/186 (41%)
gcy-22	NP_508018.2	Periplasmic_Binding_Protein_Type_1	28..408	CDD:299141	32/109 (29%)
		ANF_receptor	48..399	CDD:279440	29/100 (29%)
		PKc_like	553..795	CDD:304357	33/241 (14%)
		HNOBA	<791..852	CDD:285003	19/61 (31%)
		CYCc	831..1023	CDD:214485	75/196 (38%)
		Guanylate_cyc	858..1044	CDD:278633	77/189 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910