Protein Alignment Gyc89Da and gcy-32

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_506452.5
• Gene: gcy-32 / 179887
• WormBaseID: WBGene00001552
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 709
• Identity: 186/709 - (26%)
• Similarity: 318/709 - (44%)
• Gaps: 130/709 - (18%)

  Fly     1 MYGMLYESVQHYVQEEYGVDIWRKVCHIIDCKHNSFKT------HQIYPDKLMPDIAEALSACTG 59
            |:|.::||::..|...||.|.|.:|     .:.:.|::      :..|.|.....:.:::|....
 Worm     1 MFGFIHESIRQLVIRNYGEDTWTQV-----LERSGFESGKENIMNHYYSDTDTYVLVDSVSLVLK 60

  Fly    60 ESFDFCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPK--MKSPSMQLT 122
            .:.|.....:|...:.:....|:|:::||.......||.::|::|..:.....|  ::.||.:..
 Worm    61 VTKDQVWEMYGGFLITYSMEIGWDELVRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPSFRCE 125

  Fly   123 NMDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQNDISGGTAGPIKLTDGPLT 187
            ...|...::.|.:.|.|:...:.|.:.|||:..:.|:|...|       .|.|...:.:.:|.
 Worm   126 ETPDGTLLLHYFTGRPGLYHIVKGVVKEVAKRVFDLDITLVV-------QGRTQRSVHMNNGE-- 181

  Fly   188 VIVKYRLDFDNREYMAKRVNTEAHP--------------SQLKMPT-------VKLDVFLDLFPF 231
                 |::    |::...:|..:.|              :....||       :.||.|....|:
 Worm   182 -----RVE----EHVVFLINNLSEPRRDSEGSEVSLLTSTNANFPTIVDDTLGISLDDFSKALPY 237

  Fly   232 TFVLNHDMKITHAGEKIVETWIMHNPGANPKSFIGTHVMDLFQCRRPKDTTIDWDTLIQMRAVLF 296
            .||::...|:...|.:      :||...|.....||.::.:|:..||: ..:|::.:......:|
 Worm   238 HFVIDESCKLVQCGSE------LHNHIPNELLQPGTPILRIFEINRPQ-IPLDFENICNFINAVF 295

  Fly   297 EFEL----IRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDDDESAREDEI 357
            ..::    ::..|..|.....|..:.|..||...||.
 Worm   296 VLQVKTSPLKKKHMDAMSQEELKQEMETLDEDATNEL---------------------------- 332

  Fly   358 DPATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELV 422
                     :|| ..:.|||||..:.....:|:||||.:.:::||...|:.|..:..|..:|:|:
 Worm   333 ---------TQG-HHLKLKGQMMLLASKKHIIYLCSPYVTSINELMQYGMRLTAMPLHDATRDLI 387

  Fly   423 MAGWQHCSKLEI--MFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQ 485
            :...|..|.:|:  ..|...::.:.:.:.|||.   :::.|.:|..|:||.||::: ||.|.:..
 Worm   388 LLNQQRLSDVEVNLQLEANNEQLETMTRELELE---RQKTDSILKDMLPRRIAQQL-LSGEHIEA 448

  Fly   486 SFEEVSVIFLEVMNVYDEGLNSIQGAM------QTVNTLNKVFSALDEEIISPFVYKVETVGMVY 544
            ...|.:|:|.:        |.:.|.|:      ..||.||::|..||..::...|||||||...|
 Worm   449 CEHEATVMFCD--------LPAFQQAIPQCSPKDIVNMLNEIFRKLDRIVVIRGVYKVETVSDSY 505

  Fly   545 MAVSGAPDVNPLHAEHACDLALRVMKKFKAHDMGD------VAIRVGINSGPVVAGVVGQKVPRY 603
            |||||.||..|.|||:.|.:||.:|  ::|..:.|      ..:|:||:||.:.|||||...|:|
 Worm   506 MAVSGIPDYTPEHAENMCHVALGMM--WEARSVIDPVSKTPFLLRIGIHSGTITAGVVGTVHPKY 568

  Fly   604 CLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVG-YKVESRGTVQVKGKGDMETYWL 661
            ||||:||..||:|||.....|||.||:...|..:.| ::...||.:.||.:|..|||:|
 Worm   569 CLFGETVTLASQMESLGMAGKIQCSKWAYQKAMETGRFEFSPRGRIDVKQRGLTETYFL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	35/166 (21%)
		HNOBA	218..476	CDD:462234	61/270 (23%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	77/190 (41%)
gcy-32	NP_506452.5	HNOB	3..167	CDD:462233	36/168 (21%)
		HNOBA	226..440	CDD:462234	59/261 (23%)
		CYCc	419..608	CDD:214485	79/202 (39%)