Protein Alignment Gyc89Da and gucy2f

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_571939.2
• Gene: gucy2f / 140424
• ZFINID: ZDB-GENE-011128-7
• Length: 1107
• Species: Danio rerio
• Alignment Length: 742
• Identity: 173/742 - (23%)
• Similarity: 293/742 - (39%)
• Gaps: 190/742 - (25%)

  Fly    15 EEYGVDIWRKVCHIIDCKHN--SFKTHQI-YPDKLMPDI-----AEALSACT-GESFDFCMNFFG 70
            |.:|..::|  |.::|...:  .|....| :|.:..|..     .|..:.|| |....:.:..|.
Zfish   417 EAWGTQLYR--CFLVDMTSDLVLFAGRFIHFPGESPPPSDSRCWFEDNAICTGGVDIIYVIIAFV 479

  Fly    71 RCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLI------------MRFTYPKMKSPSMQLTN 123
            ...:....:.|....||          :.|..|.||            :.|..|::....:.|.:
Zfish   480 IVLIIVLGSIGLSLFIR----------RRIQQIQLIKGPNRILLTLEDLTFINPQLSKRKITLED 534

  Fly   124 MDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQNDISGGTAGPIKLTDGPLTV 188
            :.|:.:.|..:|  ||.....:..|.....|                     ...:.:.:|....
Zfish   535 LSDSKSYIEEKS--TGDRSRSVNSMATATHE---------------------TSNVAVYEGDWVW 576

  Fly   189 IVKYRLDFDNREYMAKRVNTEAHPSQLKMPTVKLDVFLDLFPFTFVLNHDMKITHAGEKIVETWI 253
            :.|:               ||.|..::|..|.|:          |....|::
Zfish   577 LKKF---------------TEGHFKEVKQSTTKI----------FTKMKDLR------------- 603

  Fly   254 MHNPGANPKSFIGTHV-MDLF-----QCRRPK--------DTTIDW--------DTLIQMRAVLF 296
              |...||  |:|... .::|     .|.|..        |..:||        |.:..|:.:..
Zfish   604 --NENVNP--FLGFFTDCEMFAIVTEHCSRGSLHDLLRNDDVKLDWMFKSSLVLDLIKGMKYLHH 664

  Fly   297 -EFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDD-DESAREDEIDP 359
             ||...|........|....:...:|...::.|.|     ||.:  |:.|.:| ..:|.|...||
Zfish   665 REFPHGRLKSRNCVVDGRFVLKITDYGYNEILETQ-----KAPK--ETLPPEDLFWTAPEHLRDP 722

  Fly   360 ATGERRSSQG--------LRSILLKGQMF---------YIKDVDSLIFLCSPLI----------- 396
            .:..:.:.:|        |:.::::|..:         .|:.|.....:|.|.:
Zfish   723 ESPRKGTYKGDVYSFAIILQEVVVRGAPYCMLGLSPEEIIRKVKKPPPMCRPTVAPDQAPLECIQ 787

  Fly   397 -------------ENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEK 448
                         ...|::......:|......:...::....|:.|.||.:.   .:|::|||.
Zfish   788 LMKQCWSEQPDRRPPFDQIFDQFKLINKGKKTNIIDSMLRMLEQYSSNLEDLI---RERTEELEV 849

  Fly   449 SLELADSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQ 513
            .       |::.::||..|:|..:||.::.......:.|::|::.|.:::..  ..::|:...::
Zfish   850 E-------KQRTEKLLSEMLPPSVAEALKTGASVEPEYFDQVTIYFSDIVGF--TTISSLSDPIE 905

  Fly   514 TVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMK---KFKA 574
            .|:.||.::|..|..:.|..||||||:|..||..||.|..| ..||....:::|.::.   .||.
Zfish   906 VVDLLNDLYSLFDAVLGSHDVYKVETIGDAYMVASGLPKKNGNKHAAEIANMSLNILSSVGSFKM 970

  Fly   575 HDMGD--VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQ 637
            ..|.:  |.||:||:|||.||||||..:||||||||||||||||||:..|::|.::..|...:|.
Zfish   971 RHMPEVPVRIRIGIHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNISTVQILRS 1035

  Fly   638 V--GYKVESRGTVQVKGKGDMETYWLL 662
            :  |||::.||..::||||..|||||:
Zfish  1036 LNDGYKIDVRGKTELKGKGIEETYWLV 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	31/166 (19%)
		HNOBA	218..476	CDD:462234	57/322 (18%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	78/184 (42%)
gucy2f	NP_571939.2	PBP1_sensory_GC_DEF-like	59..440	CDD:380594	6/24 (25%)
		PK_GC-2D	551..816	CDD:270945	50/334 (15%)
		HNOBA	<825..870	CDD:462234	15/54 (28%)
		CYCc	850..1042	CDD:214485	74/200 (37%)