DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc89Da and Adcy3

DIOPT Version :9

Sequence 1:NP_001036718.1 Gene:Gyc89Da / 42001 FlyBaseID:FBgn0038435 Length:667 Species:Drosophila melanogaster
Sequence 2:NP_612178.2 Gene:Adcy3 / 104111 MGIID:99675 Length:1145 Species:Mus musculus


Alignment Length:442 Identity:110/442 - (24%)
Similarity:185/442 - (41%) Gaps:110/442 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   260 NPKSFIGTHVMDLFQCRRPKDTTIDWDTLIQM-RAVLFEFELIRTGHNRAAYDAVLNM-----DF 318
            |||.:....|:.|.       .||   .|:|: ..|.....|:.||...|     ||:     .|
Mouse   749 NPKYYNYVAVLSLI-------ATI---MLVQVSHMVKLTLMLLVTGAVTA-----LNLYAWCPVF 798

  Fly   319 ENYDEMDLNEAQT--MALAKAQEFSESHPVDDDESAREDEIDPATGERRSSQGLRSILLKGQMFY 381
            :.||.....|..:  :||.|.|..:.......|...      |....:.|...:..:::....::
Mouse   799 DEYDHKRFQEKDSPMVALEKMQVLATPGLNGTDSRL------PLVPSKYSMTVMMFVMMLSFYYF 857

  Fly   382 IKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDEL 446
            .:.|:.                             |:|.|.:  |    |:|:        .|:.
Mouse   858 SRHVEK-----------------------------LARTLFL--W----KIEV--------HDQK 879

  Fly   447 EKSLELADSWKRQGDELLYSMIPRPIAERM----RLSEEQVCQSFEEVSVIFLEVMNVYD----E 503
            |:..|:    :|..:.|:.:|:|..:|...    :..||...||::|:.|:|..:.|..|    |
Mouse   880 ERVYEM----RRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEE 940

  Fly   504 GLNSIQGAMQTVNTLNKVFSALDEEIISP---FVYKVETVGMVYMAVSG-APDVNP--------- 555
            .:|:  |.::.:..||::.|..|..:.:|   .:.|::|:|..|||.|| .||||.         
Mouse   941 SINN--GGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKE 1003

  Fly   556 --------LHAEHACDLALRV---MKKFKAHDMGDVAIRVGINSGPVVAGVVGQKVPRYCLFGDT 609
                    .|.....|.||.:   :.........:..:|:|:|.|.|:|||:|.:.|.|.::|:|
Mouse  1004 EKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNT 1068

  Fly   610 VNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVKGKGDMETYWL 661
            ||.||||||:.....||:.:.|...:|:.|::...||.:.|||||::.|::|
Mouse  1069 VNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFL 1120

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc89DaNP_001036718.1 HNOB 2..161 CDD:285002
HNOBA 218..476 CDD:285003 42/223 (19%)
CYCc 457..643 CDD:214485 64/217 (29%)
Guanylate_cyc 485..662 CDD:278633 66/205 (32%)
Adcy3NP_612178.2 AC_N <44..303 CDD:318454
Guanylate_cyc 310..494 CDD:306677
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 504..564
Guanylate_cyc 915..1122 CDD:306677 66/208 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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