Protein Alignment Gyc89Da and gucy1b2

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_017949923.2
• Gene: gucy1b2 / 100496697
• XenbaseID: XB-GENE-989428
• Length: 781
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 189/715 - (26%)
• Similarity: 328/715 - (45%)
• Gaps: 130/715 - (18%)

  Fly     1 MYGMLYESVQHYVQEEYGVDIWRKVCHIIDCKHNSFKTHQIYPDKLMPDIAEALSACTGESFDFC 65
            |||.:...::..|.|::|.:.| .:..|.....::|.|:::|.|::...:.|.:......|.:..
 Frog    20 MYGFINTCLKSLVIEKFGEETW-DLLRIQTGVQDTFMTYEVYKDEITLQLVEKVCNMLDVSPEAV 83

  Fly    66 MNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPKMKSPSMQLTNMDDNGAV 130
            :..||..|..|....|||.|:|:.|....:|:.::|.:|..:..:|.:|.:||.::....|....
 Frog    84 LRQFGEYFFEFCKKSGYDHMLRTLGGDLYEFIANLDALHSYLSLSYQEMNAPSFRVEMNGDGSMH 148

  Fly   131 ILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQND--------------ISGGTAGPIKL 181
            :.|.|.|.|:...:.|.|..||.:|:..||...:| ||:|              ::...|.|.|.
 Frog   149 LHYYSDRRGLCHIVPGIMGAVAMDFFKTEISMEII-SQSDEEERTGKKEHIVFLVTQKPAFPPKC 212

  Fly   182 TDGPLTVI--VKYRLDFDN--REYMAKRVNTEAHPSQLK--------------------MPTVKL 222
            ...|..|.  :|.: .|:|  .:|..::......|.:..                    .|....
 Frog   213 PTKPPLVSRGIKNK-SFENPYNKYRDRKNQVSVCPVKKNHWAMIRGIVQLGKGRMLRGFRPVYPK 276

  Fly   223 DVFLDL------FPFTFVLNHDMKITHAG---EKIVETWIMHNPGANPKSFIGTHVMDLFQCRRP 278
            |:.:|:      .||..|.:.:::|..||   :|||       ||
 Frog   277 DLCVDVETFCKGLPFHIVFDEELRIKQAGVSIQKIV-------PG-------------------- 314

  Fly   279 KDTTIDWDTLIQMRAVLFEFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKAQEFSES 343
                                 |..||.....|.:.::.:.            |:.::..::|..|
 Frog   315 ---------------------LQTTGIRLDQYFSTVHPEV------------TLTISNVRKFINS 346

  Fly   344 HPVDDDESAREDEIDPATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLY 408
            ..|    ...:.|:.|.:...|.     .:.|:|||.:::.::.:::|||||:..|.||....::
 Frog   347 QFV----FRTKREMMPESWRDRP-----MLELRGQMIWMEKLECMLYLCSPLLRTLHELEERQMH 402

  Fly   409 LNDLNPHGLSRELVMAGWQHCSKLEI--MFEKEEQRSDELEKSLELADSWKRQGDELLYSMIPRP 471
            ::|:.||.::|:|::...|..:::|:  ..|::::....|.|.||   ..|::.:.|||:|:|:.
 Frog   403 ISDIAPHDVTRDLILLNQQRLAEMELSNQLERKKEELRILSKHLE---EEKKKTELLLYAMLPKH 464

  Fly   472 IAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEIISPFVYK 536
            :|.:::..:......|:|.:::|.:|:..  ..:.:....:|.|..||.::...|.......|||
 Frog   465 VANQLKEGKRVEAGEFKECTILFSDVVTF--TNICAQCEPIQIVFMLNSMYLRFDRLTTVHDVYK 527

  Fly   537 VETVGMVYMAVSGAPDVNPLHAEHACDLALRVM---KKFKAHDMGD-VAIRVGINSGPVVAGVVG 597
            |||:|..||.|.|.|.....|||...:.||.::   |:.|....|: :.||||::||||:|||||
 Frog   528 VETIGDAYMVVGGVPVPVSSHAERVANFALGMILMAKQVKNPVNGNPIQIRVGLHSGPVLAGVVG 592

  Fly   598 QKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVKGKGDMETYWLL 662
            :|:||||||||||||||||||...|.||.:|......::...:::..||.:.|||||.|.||:|:
 Frog   593 EKMPRYCLFGDTVNTASRMESHGVPNKIHISPTVYRYLKGKNFEMTERGEIDVKGKGRMRTYFLI 657

  Fly   663  662
             Frog   658  657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	41/158 (26%)
		HNOBA	218..476	CDD:285003	56/268 (21%)
		CYCc	457..643	CDD:214485	72/189 (38%)
		Guanylate_cyc	485..662	CDD:278633	75/180 (42%)
gucy1b2	XP_017949923.2	HNOB	21..182	CDD:400167	42/161 (26%)
		HNOBA	280..469	CDD:400168	54/260 (21%)
		Guanylate_cyc	475..657	CDD:306677	75/183 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920