Protein Alignment Gyc89Da and gucy1a1

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_002933521.3
• Gene: gucy1a1 / 100496677
• XenbaseID: XB-GENE-983418
• Length: 700
• Species: Xenopus tropicalis
• Alignment Length: 659
• Identity: 156/659 - (23%)
• Similarity: 261/659 - (39%)
• Gaps: 202/659 - (30%)

  Fly     9 VQHYVQEEYGVDIWRKVCHIIDCKH-------------NSFKTHQIYPDKLMPDIAEALSACTGE 60
            |:| |:|..|.:::| :|:..| :|             |||.||.....:     :..|..|:|
 Frog   147 VEH-VKETLGDELFR-ICYEED-EHVLQVVAGTLKDFLNSFGTHLKQSGQ-----SRTLEECSG- 202

  Fly    61 SFDFCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPKMKSPSMQLTNMD 125
                                      ...|...|  |:. |..:|.:.:.:|...:| :.|..:.
 Frog   203 --------------------------LEEGSILC--LEK-DQDYLNVYYFFPNNITP-LILPGII 237

  Fly   126 DNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQNDISGGTAGPIKLTDGPLTVIV 190
            ...|.||:.:                       |::..:|            |...:||.
 Frog   238 RAAACILFET-----------------------EVEVRLI------------PHSCSDGN----- 262

  Fly   191 KYRLDFDNREYMAKRV---NTEAHPSQLKMPT---VKLDVFLDLFPFTFVLNHDMKITHAGEKIV 249
                ||....|:...|   ||....|..|..:   :...:|...|||.|:.:.||.:..
 Frog   263 ----DFIKEPYLLYSVQVKNTRPSLSPSKPQSYVVIPASIFCKTFPFHFMFDKDMTMLQ------ 317

  Fly   250 ETWIMHNPGANPKSFIGTHVMDLFQCRR-PKDTTIDWDTLIQMRAVLFEFELIRTGHNRAAYDAV 313
                           ||..|..|...|. |:.:|.:....|....:...|..|.|         :
 Frog   318 ---------------IGNGVKRLLNWRDIPRKSTFEEYFEILSPKISCTFSGILT---------M 358

  Fly   314 LNMDFENYDEMDLNEAQTMALAKAQEFSESHPVDDDESAREDEIDPATGERRSSQGLRSILLKGQ 378
            |||.|                                     .|...|.:..:.|..:::.||||
 Frog   359 LNMQF-------------------------------------VIRVKTWDSTTDQTSKAMNLKGQ 386

  Fly   379 MFYIKDVDSLIFLCSPLIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRS 443
            |.|:.:..:::||.||.::.|::..|.||||:|:..|...|::|:.|.|..::     :..::|.
 Frog   387 MIYVFESSAILFLGSPCVDRLEDFTGQGLYLSDIPIHNALRDVVLTGEQARAQ-----DGLKKRL 446

  Fly   444 DELEKSLELA----DSWKRQGDELLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEG 504
            .:|:.:||.|    :..|::..:||:|:.|..:|:::...|....:.|..|:::|.:::     |
 Frog   447 GKLKATLEQAHQALEEEKKKTVDLLFSIFPGEVAQQLWQGETVQAKKFNNVTMLFSDIV-----G 506

  Fly   505 LNSI---QGAMQTVNTLNKVFSALDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAE---HACD 563
            ..:|   ...||.:..|:::::..|.:.....||||||:|..|....|      ||.|   ||..
 Frog   507 FTAICSHCSPMQVITMLSELYTLFDFQCGELDVYKVETIGDAYCVAGG------LHKESETHAFQ 565

  Fly   564 LALRVMKKFKAHD-----MGD-VAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDP 622
            :||..:|..:..|     .|: :.:|:|::||.|||||||.::|||||||:.|..|::.||.|.|
 Frog   566 VALMALKMMELSDEVMSPHGEQIKMRIGLHSGSVVAGVVGVRMPRYCLFGNNVTLANKFESCSVP 630

  Fly   623 WKIQLSKYT 631
            .||.:|..|
 Frog   631 RKINVSPTT 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	29/164 (18%)
		HNOBA	218..476	CDD:285003	58/265 (22%)
		CYCc	457..643	CDD:214485	63/187 (34%)
		Guanylate_cyc	485..662	CDD:278633	56/159 (35%)
gucy1a1	XP_002933521.3	HNOBA	294..483	CDD:400168	58/260 (22%)
		Guanylate_cyc	489..676	CDD:306677	56/162 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920