Protein Alignment Gyc89Da and gucy2g

DIOPT Version :9

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_009305067.2
• Gene: gucy2g / 100333350
• ZFINID: ZDB-GENE-130531-70
• Length: 1127
• Species: Danio rerio
• Alignment Length: 728
• Identity: 183/728 - (25%)
• Similarity: 295/728 - (40%)
• Gaps: 213/728 - (29%)

  Fly    74 VRFFSNFGYD---KMIRSTGRY----------------------FCDFLQS-------------- 99
            ::|.|...:|   |||:.|.|:                      .|::|.:
Zfish   414 IQFVSVLDFDSHTKMIKPTLRFSNIVWQNGKPPTDNPSCGFDNELCEWLDNEISLLVLLVALPLI 478

  Fly   100 -IDNIHLIMRFTYPKMKSPSMQLTNMDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGLEIKAY 163
             :..:.||...|..|::..|    .:|::...::..|..|            :.||..|.:|.:.
Zfish   479 GVAAVSLITLLTLQKLRLQS----RLDESNWWLINYSDIT------------ILREPKGTQILSV 527

  Fly   164 VIESQNDISGG-----------TAGPIKLTDGPLTVIVKYRLDFDNREYMAKRVNTEAHPSQLKM 217
            ........|||           |...|..|.|.          |...|...|.:..:..| .:|.
Zfish   528 NTTPSKCGSGGSQSMLSSNSCNTREAIYATVGL----------FQGNEVGIKYLKNQIIP-DIKK 581

  Fly   218 PTVKLDVFLDLFPFTFVLNHDMKITHAGEKI----VETWIMHNPGANPKSFIGTHVMDLFQCRRP 278
            |::..:     |.....:.|:..:...|..|    |...:.:....:.|..:|.|.:||
Zfish   582 PSIIAE-----FNMLKEMKHENLVQFFGVCIDPPNVCIVMQYCKKGSLKDVLGNHEIDL------ 635

  Fly   279 KDTTIDWDTLIQMRAVLFEFELIRTGHNRAAYDAVLNMDFENYDEM----DLNEAQTMALAKAQ- 338
                 ||         :|:...        |||.|..|::.:...:    :|..:..:..::.|
Zfish   636 -----DW---------MFKLSF--------AYDIVNGMEYIHKSSLKSHGNLRPSTCLVDSRLQI 678

  Fly   339 --------EF--SESHPVDDDESAREDEIDPATGERRSSQGLRSILL------KGQMFYIKDVDS 387
                    ||  ...|.:...:|.:.:|:     ...:.:.||.|..      ||      ||.|
Zfish   679 KLSGFGLWEFKCGTKHRLIPLDSPKYEEM-----YWTAPEFLREIFYPFNGTQKG------DVYS 732

  Fly   388 LIFLCSPLIENLDELHGIGLYLN-DLNPHGLSRE-------------------------LVMAGW 426
            ...:...||.:.:    :|.|.: .|.|..:.::                         |:.|.|
Zfish   733 FAIIIRELIYSTE----VGPYHDVHLEPKEIIKQLRTPMSEEPLRPTLSADICDERLIPLIKACW 793

  Fly   427 -----------------------QHCSKLEIMFEKEEQRSDELEKSLELADSW----KRQGDELL 464
                                   .|.:.|:.|..|.|:.::.||:.:|...|.    |.:.|:||
Zfish   794 SENPDHRPPFGSIRRQLRDACPESHANILDNMVNKLEKYANHLEEVVEERTSQLTVEKSRADKLL 858

  Fly   465 YSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQGAMQTVNTLNKVFSALDEEI 529
            .||:||.||:::...:....:|:|.|::.|.:::..  ..:.|:..|::.|..||.::|..|:.|
Zfish   859 SSMLPRYIADQLMAGKSVEPRSYEMVTIFFSDIVGF--TTMCSVSSALEVVTLLNDLYSLFDDII 921

  Fly   530 ISPFVYKVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVM---KKFKAHDMGD--VAIRVGINS 588
            ....||||||:|..||..||.|..| .||||....:||..:   |:||...:.:  :|:|:||||
Zfish   922 KLYDVYKVETIGDAYMVASGLPISNGTLHAEEISTMALHFLSSIKRFKIRHLPNERLALRIGINS 986

  Fly   589 GPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVG-YKVESRGTVQVKG 652
            |||||||||..:||||||||||||||||||:|.|.||.:|:.|.|.:..:| :::|.||.:::||
Zfish   987 GPVVAGVVGSTMPRYCLFGDTVNTASRMESNSLPLKIHISQSTADILLTIGTFELEERGDIEIKG 1051

  Fly   653 KGDMETYWLLEGP 665
            ||..:|:|||..|
Zfish  1052 KGTQKTFWLLSKP 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002	21/126 (17%)
		HNOBA	218..476	CDD:285003	62/335 (19%)
		CYCc	457..643	CDD:214485	85/192 (44%)
		Guanylate_cyc	485..662	CDD:278633	84/183 (46%)
gucy2g	XP_009305067.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810