Protein Alignment Gyc89Da and npr2

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_009300100.2
• Gene: npr2 / 100331745
• ZFINID: ZDB-GENE-141030-2
• Length: 1048
• Species: Danio rerio
• Alignment Length: 654
• Identity: 164/654 - (25%)
• Similarity: 276/654 - (42%)
• Gaps: 178/654 - (27%)

  Fly   117 PSMQLTNMDDNGAVILYRSSRTGMSKYLIGQMTEVAREFYGL-------EIKAYVIESQNDISGG 174
            |.:.:..:....|:|::     |:|.:||.:..::.:|..|:       |::   .||.|.....
Zfish   456 PVLGIVAVGSGLALIIF-----GISSFLIYRKLKLEKELAGMLWRIRWEELQ---FESPNKYHKR 512

  Fly   175 TAGPIKLTD-----GPL-TVIVKYRLDFDNREYMAKRVNTEAHPSQLKMPTVKLDVFLDLFPFTF 233
            ....:.|:.     |.| |...||:| |....|....:....|.::.::...:        ...|
Zfish   513 AGSRLTLSQRGSSYGSLITAHGKYQL-FAKTGYFKGNLVAIKHVNKKRIELTR--------QVLF 568

  Fly   234 VLNH--DMKITHAGEKIVETWIMHNPGA---NPKSFIGTH------VMDLFQCRRPKDTTIDWDT 287
            .|.|  |::..|....|         ||   .|...|.|.      :.|:.:   .:...:||
Zfish   569 ELKHMRDVQFNHLTRFI---------GACIDPPNICIVTEYCPRGSLQDILE---NESINLDW-- 619

  Fly   288 LIQMRAVLFEFELIRTGHNRAAYDAVLNMDF-------------------ENYDEMDLNEAQTMA 333
                   :|.:.||.        |.|..|::                   ::...:.:.:....:
Zfish   620 -------MFRYSLIN--------DIVKGMNYLHNSYIGSHGNLKSSNCVVDSRFVLKITDYGLAS 669

  Fly   334 LAKAQEFSESHPVDDDESAREDEI-----DPATGERRS---SQG--LRSILLKGQMFYIKDVDSL 388
            ...:.|..:||.:...:.....|:     .|..|.::.   |.|  |:.|.|:...||::.:|
Zfish   670 FRSSCENEDSHALYAKKLWTAPELLIYDRHPPQGTQKGDVYSFGIILQEIALRNGPFYVEGMD-- 732

  Fly   389 IFLCSP--LIENLDELHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIM---------------- 435
               .||  :|:.:  .:|...|......:.          :||.:|.|:
Zfish   733 ---LSPKEIIQKV--RNGQKPYFRPTTDNS----------RHCEELTILMEGCWSEDPAERPDFS 782

  Fly   436 --------FEKE-------------EQRSDELEKSLE------LADSWKRQGDELLYSMIPRPIA 473
                    |.||             ||.::.||..:|      |.:  ||:.:.|||.::|..:|
Zfish   783 HIKVFIAKFNKEGSTSILNNLLSRMEQYANNLENLVEERTQAYLEE--KRKAENLLYQILPHSVA 845

  Fly   474 ERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQG---AMQTVNTLNKVFSALDEEIISPFVY 535
            |:::..|....::|:.|::.|.:::     |..|:..   .:|.|..||.:::..|..|.:..||
Zfish   846 EQLKRGETVQAEAFDSVTIYFSDIV-----GFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVY 905

  Fly   536 KVETVGMVYMAVSGAPDVN-PLHAEHACDLALRVMKKFKA----HDMGD-VAIRVGINSGPVVAG 594
            ||||:|..||.|||.|..| .|||.....::|.::::.|.    |...| :.:|:||::|||.||
Zfish   906 KVETIGDAYMVVSGLPVRNGKLHAREIAGMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAG 970

  Fly   595 VVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGY-KVESRGTVQVKGKGDMET 658
            |||.|:||||||||||||||||||:.:..:|.:|..|.:.:.:.|| :::.||.|::||||.|.|
Zfish   971 VVGLKMPRYCLFGDTVNTASRMESTGEALRIHMSSATKEVLDEFGYFELQLRGDVEMKGKGKMRT 1035

  Fly   659 YWLL 662
            ||||
Zfish  1036 YWLL 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	10/50 (20%)
		HNOBA	218..476	CDD:462234	60/342 (18%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	78/186 (42%)
npr2	XP_009300100.2	None