Protein Alignment Gyc89Da and gucy1a2

DIOPT Version :10

• Sequence 1: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_073780175.1
• Gene: gucy1a2 / 100330875
• ZFINID: ZDB-GENE-121023-3
• Length: 738
• Species: Danio rerio
• Alignment Length: 641
• Identity: 154/641 - (24%)
• Similarity: 262/641 - (40%)
• Gaps: 185/641 - (28%)

  Fly    64 FCMNFFGRCFVRFFSNFGYDKMIRSTGRYFCDFLQSIDNIHLIMRFTYPKMKS---PSM------ 119
            |...|||.|...      .::::|:.|....||....|.:...:|.:..:..|   ||.
Zfish   149 FGEEFFGLCLEE------NERVLRALGGNLQDFFNGFDALLEHIRTSCGRRASSEAPSFLCKDAP 207

  Fly   120 ---QLTNMDDNGA---VILY---RSSRTGMSKYLIGQMTEVAREFYGLEIKAYVIESQNDISGGT 175
               :.||. ::||   :||:   .....|::  :.|.:...||..|           |:::|...
Zfish   208 QENEETNA-ESGAGRTLILHCFNPDPTVGVA--MPGLIRAAARRIY-----------QSEVSVEE 258

  Fly   176 AGPIKL----TDGPLTVIVKYRLDFDNR----------------EYMAKRVNT-----------E 209
            |.|..|    .||.|:.        |:.                .::.:.|:|           .
Zfish   259 APPTWLHTANEDGELSA--------DSSPSSSPSPPSSSAPACLSFLIREVHTPPTSSSRSRQLS 315

  Fly   210 AHPSQLKMPTVKLDVFLDLFPFTFVLNHDMKITHAGEKIVETWIMHNPGANPKSFIGTHVMDLFQ 274
            ..|..|:   :.|..|...|||..||..:|::...||           |...::....|
Zfish   316 RSPLDLR---IGLSTFCRAFPFHLVLGSNMEVLQVGE-----------GLRKQAKTDPH------ 360

  Fly   275 CRRPKDTTIDWDTLIQMRAVLF--EFELIRTGHNRAAYDAVLNMDFENYDEMDLNEAQTMALAKA 337
                             |.:.|  .|||:         ...:...|:|           :.|..:
Zfish   361 -----------------RTLTFSNSFELV---------SPRIPCSFQN-----------ILLRLS 388

  Fly   338 QEFS-ESHPVDDDESAREDEIDPATGERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDE 401
            ..|: .:.|.......||..::                |||||.::.:.:|::||.||.::.|:|
Zfish   389 TPFTIRTRPDGSSLDCREKVME----------------LKGQMLHLPESNSIMFLGSPRVDRLEE 437

  Fly   402 LHGIGLYLNDLNPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDE----LEKSLELADSWKRQGDE 462
            |.|.||:|:|:..|..:|::::.|.|  :|.:...:|   |.|:    |||:.:..:..||:..:
Zfish   438 LMGRGLHLSDIPIHDATRDVILVGEQ--AKAQDGLKK---RMDKLKATLEKTHQALEEEKRRTVD 497

  Fly   463 LLYSMIPRPIAERMRLSEEQVCQSFEEVSVIFLEVMNVYDEGLNSIQG---AMQTVNTLNKVFSA 524
            ||||:.|..:|:|:........:.|::|:::|.:::     |..::..   .||.::.||::::.
Zfish   498 LLYSIFPGDVAQRLWQGLPVQAKKFDDVTMLFSDIV-----GFTAVCAQCTPMQVISMLNELYTR 557

  Fly   525 LDEEIISPFVYKVETVGMVYMAVSGAPDVNPLHAE---HACDLALRVMKKFK------AHDMGDV 580
            .|.:.....|||:||:|..|....|      ||.:   ||..:||..:|..:      ..|...:
Zfish   558 FDYQCGILDVYKIETIGDAYCVAGG------LHRKIDSHAKPIALMALKMMELSEEVLTPDGKPI 616

  Fly   581 AIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVR 636
            .:|:||:||.|:|||||..:|||||||:.|..||:.||.|.|..|.:|..|...:|
Zfish   617 KLRIGIHSGSVLAGVVGVMMPRYCLFGNNVTLASKFESGSHPRCINVSPTTYQLLR 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233	25/114 (22%)
		HNOBA	218..476	CDD:462234	61/264 (23%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	54/164 (33%)
gucy1a2	XP_073780175.1	None