Protein Alignment CSN5 and MPND

DIOPT Version :9

• Sequence 1: NP_477442.1
• Gene: CSN5 / 42000
• FlyBaseID: FBgn0027053
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001287791.1
• Gene: MPND / 84954
• HGNCID: 25934
• Length: 501
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 62/289 - (21%)
• Similarity: 112/289 - (38%)
• Gaps: 86/289 - (29%)

  Fly    51 DIKISALALLKMVMHA---RSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEG----TETRVNAQA 108
            ::.:|:..|..:..|:   ||    ||:|.:.|:.:.|:.::....|.|...    .||....:.
Human   271 NVAVSSNVLFLLDFHSHLTRS----EVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIEE 331

  Fly   109 QAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQ----------EPFV 163
            :.|:.:..         |....||||||||......|..|:..||   .||          :|.:
Human   332 EIYQSLFL---------RGLSLVGWYHSHPHSPALPSLQDIDAQM---DYQLRLQGSSNGFQPCL 384

  Fly   164 AIVVDPVRTVSAG-KVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHCKQYYPLEISYFK 227
            |::..|..:.:.| :..:..|...|    ||.:.||:| .||::              :|::|.:
Human   385 ALLCSPYYSGNPGPESKISPFWVMP----PPEQRPSDY-GIPMD--------------VEMAYVQ 430

  Fly   228 SALDRRLLDSLWNKYWVNTLGSSGLLTNTEYTTG--QIMDLSEKLEQSENFLGRGTDVNEKRSED 290
               |..|.:.:.::          ::...|:..|  .::.|.|...|...:|            |
Human   431 ---DSFLTNDILHE----------MMLLVEFYKGSPDLVRLQEPWSQEHTYL------------D 470

  Fly   291 KL-----SKATRDCSR-STIELIHGLMAQ 313
            ||     |:..:|.|. ..:|.:.|::.|
Human   471 KLKISLASRTPKDQSLCHVLEQVCGVLKQ 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	59/279 (21%)
MPND	NP_001287791.1	MPN_2A_DUB	266..450	CDD:163698	48/226 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810