DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN5 and CSN5A

DIOPT Version :9

Sequence 1:	NP_477442.1	Gene:	CSN5 / 42000	FlyBaseID:	FBgn0027053	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_173705.1	Gene:	CSN5A / 838899	AraportID:	AT1G22920	Length:	357	Species:	Arabidopsis thaliana

Alignment Length:	339	Identity:	218/339 - (64%)
Similarity:	261/339 - (76%)	Gaps:	16/339 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SDAAQKTWELENNIQTLP------SCDEIFRYDAEQQRQIIDAKPWEKDPHFFKDIKISALALLK 61
            |..|:|||||||||  ||      :.|.||.||...|.:|...|||..||::||.:.||||||||
plant     6 SAIARKTWELENNI--LPVEPTDSASDSIFHYDDASQAKIQQEKPWASDPNYFKRVHISALALLK 68

  Fly    62 MVMHARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGR 126
            ||:|||||||:|:||||.||.|.:|:||||||||||||||||||||:.|||||..|.:.:|..||
plant    69 MVVHARSGGTIEIMGLMQGKTEGDTIIVMDAFALPVEGTETRVNAQSDAYEYMVEYSQTSKLAGR 133

  Fly   127 MEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSAGKVCLGAFRTYPKGYK 191
            :|:.||||||||||||||||||||||||||.|||||:|:|:||.||||||||.:|||||||:|:|
plant   134 LENVVGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGHK 198

  Fly   192 PPNEEPSEYQTIPLNKIEDFGVHCKQYYPLEISYFKSALDRRLLDSLWNKYWVNTLGSSGLLTNT 256
            ..::..||||||||||||||||||||||.|:|:||||:||..|||.||||||||||.||.||.|.
plant   199 ISDDHVSEYQTIPLNKIEDFGVHCKQYYSLDITYFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNG 263

  Fly   257 EYTTGQIMDLSEKLEQSENFL------GRGTDVNEKRSED--KLSKATRDCSRSTIELIHGLMAQ 313
            :|..|||.||:|||||:|:.|      |.....:::|.||  :|:|.|||.::.|:|.:||||:|
plant   264 DYVAGQISDLAEKLEQAESQLANSRYGGIAPAGHQRRKEDEPQLAKITRDSAKITVEQVHGLMSQ 328

  Fly   314 IVKDKLFNKVGLGK 327
            ::||.|||.....|
plant   329 VIKDILFNSARQSK 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	185/271 (68%)
CSN5A	NP_173705.1	MPN_RPN11_CSN5	48..321	CDD:163700	185/272 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	186	1.000	Domainoid score	I988
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55992
Inparanoid	1	1.050	441	1.000	Inparanoid score	I404
OMA	1	1.010	-	-		QHG54454
OrthoDB	1	1.010	-	-		D1031881at2759
OrthoFinder	1	1.000	-	-		FOG0002867
OrthoInspector	1	1.000	-	-		otm3541
orthoMCL	1	0.900	-	-		OOG6_102889
Panther	1	1.100	-	-	LDO	PTHR10410
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840