Protein Alignment CSN5 and Stambp

DIOPT Version :10

• Sequence 1: NP_477442.1
• Gene: CSN5 / 42000
• FlyBaseID: FBgn0027053
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_077201.1
• Gene: Stambp / 70527
• MGIID: 1917777
• Length: 424
• Species: Mus musculus
• Alignment Length: 234
• Identity: 45/234 - (19%)
• Similarity: 78/234 - (33%)
• Gaps: 88/234 - (37%)

  Fly    20 PSCDEIFRYDAEQQRQIIDAKPWEKDPHFFKDIKISALALLKMV-------------------MH 65
            |.|:...|          .|||    |...:.:|..||::::.|                   :.
Mouse   219 PDCNTGMR----------PAKP----PVVDRSLKPGALSVIENVPTIEGLRHIVVPRNLCSEFLQ 269

  Fly    66 ARSGGT---LEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGRM 127
            ..|..|   :|..|::.||:..|...:          |...:..|....:|  .:.|..:|:..|
Mouse   270 LASANTAKGIETCGVLCGKLMRNEFTI----------THVLIPRQNGGPDY--CHTENEEEIFFM 322

  Fly   128 EH-----AVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSAGKVCLGAFRTYP 187
            :.     .:||.|:||....:||.:|:.|....|......:|||..|
Mouse   323 QDDLGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSP------------------ 369

  Fly   188 KGYKPPNEEPSEYQTIPLNKIEDFGVH----CKQ--YYP 220
                       ::|.....|:.|:|:.    |:|  ::|
Mouse   370 -----------KFQETGFFKLTDYGLQEISTCRQKGFHP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	40/213 (19%)
Stambp	NP_077201.1	Interaction with CHMP3. /evidence=ECO:0000250|UniProtKB:O95630	1..127
		USP8_dimer	7..117	CDD:462647
		Interaction with STAM. /evidence=ECO:0000250|UniProtKB:O95630	227..231		3/7 (43%)
		MPN_AMSH_like	254..424	CDD:163697	34/185 (18%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	335..348		5/12 (42%)