DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CSN5 and Mpnd

DIOPT Version :9

Sequence 1:	NP_477442.1	Gene:	CSN5 / 42000	FlyBaseID:	FBgn0027053	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_080806.4	Gene:	Mpnd / 68047	MGIID:	1915297	Length:	487	Species:	Mus musculus

Alignment Length:	176	Identity:	45/176 - (25%)
Similarity:	73/176 - (41%)	Gaps:	43/176 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DIKISALALLKMVMH---ARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEG----TETRVNAQA 108
            ::.:|:..|..:..|   .||    ||:|.:.|:.:.|..::....|.|...    |:|....:.
Mouse   257 NVAVSSNVLFLLDFHCHLTRS----EVVGYLGGRWDINNQMLTVLRAFPCRSRLGDTDTAATVEE 317

  Fly   109 QAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQ----------EPFV 163
            :.|:.:..         |....||||||||......|..|:..||   .||          :|.:
Mouse   318 EIYQVLFL---------RGLSLVGWYHSHPHSPAVPSLQDIDAQM---EYQLRLQGSSNGFQPCL 370

  Fly   164 AIVVDPVRTVSAG---KVCLGAFRTYPKGYKPPNEEPSEYQTIPLN 206
            |::..|..:.:.|   |:|  .|...|    ||.:.||:| .||::
Mouse   371 ALLCSPYYSGNPGPESKIC--PFWVMP----PPEQRPSDY-GIPMD 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	45/176 (26%)
Mpnd	NP_080806.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..217
		MPN_2A_DUB	252..436	CDD:163698	45/176 (26%)
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	335..348		5/12 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810