DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN5 and Eif3f

DIOPT Version :9

Sequence 1:	NP_477442.1	Gene:	CSN5 / 42000	FlyBaseID:	FBgn0027053	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_079620.2	Gene:	Eif3f / 66085	MGIID:	1913335	Length:	361	Species:	Mus musculus

Alignment Length:	275	Identity:	61/275 - (22%)
Similarity:	111/275 - (40%)	Gaps:	59/275 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 IKISALALLKMV--MHARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYM 114
            :::..:.|..:|  ...|:.|...|:|.:||.|:.:::.|.:.|::|...:|..|   |...|:.
Mouse    96 VRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEV---AVDMEFA 157

  Fly   115 TAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVS--TQMLNQTYQEPFVAIVVDPVR-TVSAG 176
            ....|..|:|...|..:|||         .:|.|::  :.::::.|...    ..:|:. ||..|
Mouse   158 KNMYELHKKVSPNELILGWY---------ATGHDITEHSVLIHEYYSRE----APNPIHLTVDTG 209

  Fly   177 KVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHCKQYYPLEISYFKSALDRRLLDSLWNK 241
               |...|...|.|      .|....:|...:   ||   .:.||.:.|.....:|..:|
Mouse   210 ---LQHGRMSIKAY------VSTLMGVPGRTM---GV---MFTPLTVKYAYYDTERIGVD----- 254

  Fly   242 YWVNTLGSSGLLTNTEYTTGQIMDLSEKLEQSENFLGRGTDVNE---KRSEDKLS-KATRDCSRS 302
                      |:..|.::..:::.||..|:|......|..|...   :.:||.|| |.:.|   :
Mouse   255 ----------LIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSAD---N 306

  Fly   303 TI-ELIHGLMAQIVK 316
            |: ..:..|:.|:.|
Mouse   307 TVGRFLMSLVNQVPK 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	58/262 (22%)
Eif3f	NP_079620.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91
Eif3f	NP_079620.2	MPN_eIF3f	96..358	CDD:163695	61/275 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810