DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN5 and stambpl1

DIOPT Version :9

Sequence 1:	NP_477442.1	Gene:	CSN5 / 42000	FlyBaseID:	FBgn0027053	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	XP_009304952.1	Gene:	stambpl1 / 570542	ZFINID:	ZDB-GENE-100215-4	Length:	466	Species:	Danio rerio

Alignment Length:	159	Identity:	37/159 - (23%)
Similarity:	59/159 - (37%)	Gaps:	42/159 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEV-GRMEH----AV 131
            :|..|::.||:..|..::          |...|..|:...:|..  ||..:|: ...:|    .:
Zfish   275 IETCGVLCGKLTHNEFVL----------THVIVPKQSAGPDYCD--MENVEELFSYQDHHNLLTL 327

  Fly   132 GWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVS----------AGKVCLGAFRTY 186
            ||.|:||....:||.:|:.|....|......:|||..|....|          :|::.:..|
Zfish   328 GWIHTHPTQTAFLSSVDLHTHSSYQLMLPEAIAIVCAPKHNESFPAHQCWNGRSGRMQIERF--- 389

  Fly   187 PKGYKPPNEEPSEYQTIPLNKIEDFGVHC 215
                .||.|.||        .:.....||
Zfish   390 ----SPPLERPS--------SVHYLQAHC 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	37/159 (23%)
stambpl1	XP_009304952.1	USP8_dimer	28..130	CDD:286108
stambpl1	XP_009304952.1	MPN_AMSH_like	250..>369	CDD:163697	27/105 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810