DRSC/TRiP Functional Genomics Resources

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Protein Alignment CSN5 and Mysm1

DIOPT Version :9

Sequence 1:NP_477442.1 Gene:CSN5 / 42000 FlyBaseID:FBgn0027053 Length:327 Species:Drosophila melanogaster
Sequence 2:XP_017175747.1 Gene:Mysm1 / 320713 MGIID:2444584 Length:824 Species:Mus musculus


Alignment Length:308 Identity:73/308 - (23%)
Similarity:116/308 - (37%) Gaps:103/308 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 DSDAA-QKTWELEN---------------------NIQTLP--SCDEIFRYDAEQQRQIIDAKPW 42
            |::|| |..|.|::                     ..||..  |.:|:.|...|::.:.|.....
Mouse   475 DAEAAYQLAWRLQSMRTRRRRVRDPWGNWCDAKDLEGQTFEHLSVEEMARRKEEEKCKPIKFSKA 539

  Fly    43 EK------DP------HFFKD-------IKISALALLKMVMHARSGGTLEVMGLMLG------KV 82
            .|      ||      :||.:       :|::|.|||.|.:||.. ...||:||:.|      ||
Mouse   540 SKLPKSSLDPFQLIPCNFFSEEKQEPFQVKVAAEALLIMNLHAHV-SMAEVIGLLGGRYSEADKV 603

  Fly    83 EDNTMIVMDAFALPVEGTETRVN------AQAQAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYG 141
            .:|.::.:.| |.|.....|.:.      :|.||.|.:..         |....:|||||||.:.
Mouse   604 LENNLLQVCA-AEPCNSLSTGLQCEMDPVSQTQASETLAL---------RGYSVIGWYHSHPAFD 658

  Fly   142 CWLSGIDVSTQMLNQTY----QEPFVAIVVDPVRTVS----AGKVCL---------GAFR-TYPK 188
            ...|..|:.||...|:|    ...|:.::|.|....:    :...||         |.:| .|..
Mouse   659 PNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRSNPLPYSQITCLVISEEVSPDGTYRLPYKF 723

  Fly   189 GYKPPNEEP-------------SEYQ----TIPLNKI--EDFGVHCKQ 217
            ..:...|||             .:|:    ::|:::|  .|..:.|.|
Mouse   724 EVQQMLEEPQWELVFEKTRWIIEKYRLSNSSVPMDRIFRRDSDLTCLQ 771

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CSN5NP_477442.1 MPN_RPN11_CSN5 41..305 CDD:163700 60/245 (24%)
Mysm1XP_017175747.1 Myb_DNA-binding 116..160 CDD:365977
SWIRM 373..452 CDD:367940
MPN_2A_DUB 562..749 CDD:163698 49/197 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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