DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN5 and Mysm1

DIOPT Version :9

Sequence 1:	NP_477442.1	Gene:	CSN5 / 42000	FlyBaseID:	FBgn0027053	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	XP_008762133.1	Gene:	Mysm1 / 298247	RGDID:	1311787	Length:	811	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	68/302 - (22%)
Similarity:	110/302 - (36%)	Gaps:	96/302 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DSDAA-QKTWELEN---------------------NIQTLP--SCDEIFRYDAEQQRQIIDAKPW 42
            |::|| |..|.|::                     ..||..  |.:|:.|.:.|::.:.|.....
  Rat   467 DAEAAYQLAWRLQSMRTRRRRVRDPWGNWCDAKDLEGQTFEHLSVEELARREEEEKCKPIKFSKA 531

  Fly    43 EK------DP------HFFK-------DIKISALALLKMVMHARSGGTLEVMGLMLGKVEDNTMI 88
            .|      ||      |||.       .:|:::.|||.|.:||.. ...||:||:.|:..:...:
  Rat   532 SKLPKSSLDPFQLIPCHFFSGEKQEPFQVKVASEALLIMDLHAHV-SMAEVIGLLGGRYSEADKV 595

  Fly    89 VMDAFALPVEGTETRVN------AQAQAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGI 147
            :....|.|.....|.:.      :|.||.|.:..         |....:|||||||.:....|..
  Rat   596 LEVCAAEPCNSLSTGLQCEMDPVSQTQASETLAL---------RGCSVIGWYHSHPAFDPNPSLR 651

  Fly   148 DVSTQMLNQTY----QEPFVAIVVDPVRTVS----AGKVCL---------GAFR-TYPKGYKPPN 194
            |:.||...|:|    ...|:.::|.|....:    :...||         |.:| .|....:...
  Rat   652 DIDTQAKYQSYFSRGGAKFIGMIVSPYNRSNPLPYSQITCLVISEELSPDGTYRLPYKFEVQQML 716

  Fly   195 EEPS-----------------EYQTIPLNKI--EDFGVHCKQ 217
            |||.                 .:.::|:::|  .|..:.|.|
  Rat   717 EEPQWELVFEKTRWIIEKYRLSHSSVPMDRIFRRDSDLTCLQ 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN5	NP_477442.1	MPN_RPN11_CSN5	41..305	CDD:163700	55/239 (23%)
Mysm1	XP_008762133.1	Myb_DNA-binding	116..160	CDD:395191
		SWIRM	365..444	CDD:398234
		MPN_2A_DUB	554..736	CDD:163698	44/191 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810