DRSC/TRiP Functional Genomics Resources

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Protein Alignment CSN5 and MYSM1

DIOPT Version :9

Sequence 1:NP_477442.1 Gene:CSN5 / 42000 FlyBaseID:FBgn0027053 Length:327 Species:Drosophila melanogaster
Sequence 2:NP_001078956.1 Gene:MYSM1 / 114803 HGNCID:29401 Length:828 Species:Homo sapiens


Alignment Length:259 Identity:61/259 - (23%)
Similarity:101/259 - (38%) Gaps:72/259 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 SCDEIF-RYDAEQQRQIIDAK----------PWEKDP-HFFKD-------IKISALALLKMVMHA 66
            |.:|:. |.:.|:.|.:...|          |::..| :||.:       :|:::.|||.|.:||
Human   527 SAEELAKRREEEKGRPVKSLKVPRPTKSSFDPFQLIPCNFFSEEKQEPFQVKVASEALLIMDLHA 591

  Fly    67 RSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVN------AQAQAYEYMTAYMEAAKEVG 125
            .. ...||:||:.|:..:...:|....|.|.....|.:.      :|.||.|.:..         
Human   592 HV-SMAEVIGLLGGRYSEVDKVVEVCAAEPCNSLSTGLQCEMDPVSQTQASETLAV--------- 646

  Fly   126 RMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTY----QEPFVAIVVDPVRTVS----AGKVCL-- 180
            |....:|||||||.:....|..|:.||...|:|    ...|:.::|.|....:    :...||  
Human   647 RGFSVIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRNNPLPYSQITCLVI 711

  Fly   181 -------GAFR-TYPKGYKPPNEEPS-----------------EYQTIPLNKI--EDFGVHCKQ 217
                   |::| .|....:...|||.                 .:.::|::||  .|..:.|.|
Human   712 SEEISPDGSYRLPYKFEVQQMLEEPQWGLVFEKTRWIIEKYRLSHSSVPMDKIFRRDSDLTCLQ 775

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CSN5NP_477442.1 MPN_RPN11_CSN5 41..305 CDD:163700 55/228 (24%)
MYSM1NP_001078956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31
SANT 120..164 CDD:197842
Myb_DNA-binding 120..162 CDD:278669
SWIRM 382..461 CDD:282311
MPN_2A_DUB 571..753 CDD:163698 45/191 (24%)
JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 656..669 5/12 (42%)
LXXLL motif 774..778 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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