DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CSN5 and COPS6

DIOPT Version :9

Sequence 1:NP_477442.1 Gene:CSN5 / 42000 FlyBaseID:FBgn0027053 Length:327 Species:Drosophila melanogaster
Sequence 2:NP_006824.2 Gene:COPS6 / 10980 HGNCID:21749 Length:327 Species:Homo sapiens


Alignment Length:71 Identity:20/71 - (28%)
Similarity:35/71 - (49%) Gaps:3/71 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 MHARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGRME 128
            |.::.|..::|:|.::||.|...:.||::|.|.....|.::....   ||.....|..|:|.:..
Human    58 MRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDK---EYYYTKEEQFKQVFKEL 119

  Fly   129 HAVGWY 134
            ..:|||
Human   120 EFLGWY 125

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CSN5NP_477442.1 MPN_RPN11_CSN5 41..305 CDD:163700 20/71 (28%)
COPS6NP_006824.2 MPN_CSN6 39..321 CDD:163694 20/71 (28%)
Interaction with Vpr 211..327
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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