DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CSN5 and STAMBP

DIOPT Version :9

Sequence 1:NP_477442.1 Gene:CSN5 / 42000 FlyBaseID:FBgn0027053 Length:327 Species:Drosophila melanogaster
Sequence 2:NP_001340896.1 Gene:STAMBP / 10617 HGNCID:16950 Length:424 Species:Homo sapiens


Alignment Length:206 Identity:42/206 - (20%)
Similarity:78/206 - (37%) Gaps:49/206 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 DAAQKTWELENNIQTLPSCDEIFRYDAEQQRQIIDAKPWEKDPHFFKDIKISALALLKMVMHARS 68
            |.:.|...|.|: :::|:.|.:        |.::  .|....|.|.:            :..|.:
Human   234 DRSLKPGALSNS-ESIPTIDGL--------RHVV--VPGRLCPQFLQ------------LASANT 275

  Fly    69 GGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEAAKEVGRMEH---- 129
            ...:|..|::.||:..|...:          |...:..|:...:|...  |..:|:..::.    
Human   276 ARGVETCGILCGKLMRNEFTI----------THVLIPKQSAGSDYCNT--ENEEELFLIQDQQGL 328

  Fly   130 -AVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDP-------VRTVSAGKVCLGAFRTY 186
             .:||.|:||....:||.:|:.|....|......||||..|       .:....|...:.:.|  
Human   329 ITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESVAIVCSPKFQETGFFKLTDHGLEEISSCR-- 391

  Fly   187 PKGYKPPNEEP 197
            .||:.|.:::|
Human   392 QKGFHPHSKDP 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CSN5NP_477442.1 MPN_RPN11_CSN5 41..305 CDD:163700 35/169 (21%)
STAMBPNP_001340896.1 Interaction with CHMP3 1..127
USP8_dimer 7..114 CDD:312504
Interaction with STAM 227..231
MPN_AMSH_like 254..424 CDD:163697 36/185 (19%)
JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182 335..348 5/12 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.