DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14883 and GDE1

DIOPT Version :9

Sequence 1:	NP_650547.1	Gene:	CG14883 / 41997	FlyBaseID:	FBgn0038432	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_015215.1	Gene:	GDE1 / 855994	SGDID:	S000006031	Length:	1223	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	53/282 - (18%)
Similarity:	89/282 - (31%)	Gaps:	100/282 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 SKAAIKKCLARGYRNVLLDAGLTSCGEIVVANPTKINVAQ----------------PLVELQKLN 145
            :|||:.|.||              |.:.::.....:|.::                .|:..|::.
Yeast   307 NKAALSKSLA--------------CIDAILKVIPSLNDSEDINRRNFFHHHIIAIGKLIRKQEIL 357

  Fly   146 ITEQHPMGSQY---EAETVAPLRQLSDFLEAEAAETTVFLRLHDNSARMINELQKFMTADESFTQ 207
            ..::....|:|   |.|.|..||.|...|.|.|...:            |.|.:|......|:..
Yeast   358 SRKKKSQPSKYTNSEGEIVTDLRTLHTTLSAPAESDS------------ITEEEKSSACTLSYIL 410

  Fly   208 RTIVI------------SRSPL---AIYQLRKLKPEII-----CGLWHE---------------T 237
            ..:.|            .|:||   ..|.|.::...||     ..:|:|               |
Yeast   411 EELPIHLRPCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLT 475

  Fly   238 YLSLAILKSSTLITSIYGAIFRNIIAPVIGISVVFLSKDEINFHIADLWRNVGVRPIVYMVNSPN 302
            .|.|.:|.:....|.    :....:.|.:.:      |.....|:|..|.|.   |:::::.|
Yeast   476 PLHLCVLGAHPKTTE----VLLQSLDPNVKL------KSSSLLHLATEWNNY---PLLHVLLS-- 525

  Fly   303 EKRYFQKTMKIQYLTDSLRSEP 324
                 .|...|.|..:.|...|
Yeast   526 -----SKRFDINYQDNELHETP 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14883	NP_650547.1	UgpQ	83..319	CDD:223657	51/275 (19%)
CG14883	NP_650547.1	PI-PLCc_GDPD_SF	84..320	CDD:301322	51/276 (18%)
GDE1	NP_015215.1	COG5408	1..300	CDD:227695
		ANKYR	361..594	CDD:223738	43/214 (20%)
		ANK repeat	427..466	CDD:293786	9/38 (24%)
		ANK repeat	468..501	CDD:293786	6/36 (17%)
		ANK repeat	506..535	CDD:293786	9/38 (24%)
		Ank_2	508..603	CDD:403870	11/45 (24%)
		ANK repeat	540..569	CDD:293786	1/3 (33%)
		ANK repeat	572..603	CDD:293786
		GDPD_YPL110cp_fungi	871..1219	CDD:176548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900