DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14883 and GPCPD1

DIOPT Version :9

Sequence 1:	NP_650547.1	Gene:	CG14883 / 41997	FlyBaseID:	FBgn0038432	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_062539.1	Gene:	GPCPD1 / 56261	HGNCID:	26957	Length:	672	Species:	Homo sapiens

Alignment Length:	294	Identity:	48/294 - (16%)
Similarity:	103/294 - (35%)	Gaps:	74/294 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 YW------PIANRAAG--------FDAPENSKAAIKKCLARGYRNVLLDAGLTSCGEIVVANPTK 131
            ||      .:.:|.||        ....||:.|:::...:.|...|..|
Human   312 YWKPRIPLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFD---------------- 360

  Fly   132 INVAQPLVELQKLNITEQHPMGSQYEAETV----APLRQLS-DFLEAEAAETTVFLRLHDNSARM 191
            :::::..|.:...::|....|..:::|:.|    .|:::|: |.|:.........|:..|....:
Human   361 VHLSKDFVPVVYHDLTCCLTMKKKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDRKESV 425

  Fly   192 INELQKFMTADESFTQRTIVISRSPLAIYQLRKLKPEIIC----GLWH---ETYLSLAILKSSTL 249
            :.|...| :.::.|....:|:...|..:....::|  .||    |:|.   .||..:.:.....|
Human   426 VQEENSF-SENQPFPSLKMVLESLPEDVGFNIEIK--WICQQRDGMWDGNLSTYFDMNLFLDIIL 487

  Fly   250 ITSIYGAIFRNIIAPVIGISVVFLSKDEINFHIADLWRNVGVRPIVYMVNSPNE----------- 303
            .|.:..:..|.|:.......:..:.:.:.|.:           ||:::....:|
Human   488 KTVLENSGKRRIVFSSFDADICTMVRQKQNKY-----------PILFLTQGKSEIYPELMDLRSR 541

  Fly   304 -------KRYFQKTMKIQYLTDSLRSEPHLLMKA 330
                   ...|:..:.|...|:.|...|..:.:|
Human   542 TTPIAMSFAQFENLLGINVHTEDLLRNPSYIQEA 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14883	NP_650547.1	UgpQ	83..319	CDD:223657	43/273 (16%)
CG14883	NP_650547.1	PI-PLCc_GDPD_SF	84..320	CDD:301322	43/273 (16%)
GPCPD1	NP_062539.1	CBM20_Prei4	4..127	CDD:99888
		Substrate binding. /evidence=ECO:0000255	88..89
		GDPD_GDE5	319..611	CDD:176549	46/287 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900